ChemicalBook >> CAS DataBase List >>diABZI STING agonist-1 Tautomerism
diABZI STING agonist-1 Tautomerism
- CAS No.
- 2138498-18-5
- Chemical Name:
- diABZI STING agonist-1 Tautomerism
- Synonyms
- Tautomerism;diABZI STING agonist (Compound 3);diABZI STING agonist-1 Tautomerism;diABZI STING agonist 1 (compound 3);(E)-1-((E)-4-((E)-5-Carbamoyl-2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-7-(3-morpholinopropoxy)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-7-methoxy-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide;1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[(2E)-5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-[3-(4-morpholinyl)propoxy]-, (2E)-
- CBNumber:
- CB84844710
- Molecular Formula:
- C42H51N13O7
- Molecular Weight:
- 849.94
- MDL Number:
- MFCD31746907
- MOL File:
- 2138498-18-5.mol
Last updated:2024-11-06 15:28:16
Density | 1.44±0.1 g/cm3(Predicted) |
---|---|
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
form | Solid |
pka | 11.87±0.43(Predicted) |
color | White to light yellow |
FDA UNII | L7DUG75C36 |
diABZI STING agonist-1 Tautomerism Chemical Properties,Uses,Production
Chemical Properties
diABZI STING agonist-1 Tautomerism is a potent non-nucleoside STING agonist with great potential for the treatment of human cancers.
in vitro
diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. At a concentration of 1 μM, it demonstrates high selectivity against more than 350 kinases tested.
in vivo
diABZI STING agonist-1 (Tautomerism) (subcutaneous injection; 2.5 mg/kg) induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo.
diABZI STING agonist-1 Tautomerism Preparation Products And Raw materials
Raw materials
Preparation Products
diABZI STING agonist-1 Tautomerism Suppliers
Global( 32)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
Zepeptide Biotechnology (Shijiazhuang) Co., Ltd | +86-86-13383293380 +8613230482270 | 1919301810@qq.com | China | 141 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4589 | 55 | |
Dezhou LonWel Pharmaceutical Technology Co., Ltd. | 13761310616 | 39324283@qq.com | China | 2003 | 58 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
View Lastest Price from diABZI STING agonist-1 Tautomerism manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-11-06 | diABZI STING agonist-1 (Tautomerism)
2138498-18-5
|
US $168.00-502.00 / mg | 99.72% | 10g | TargetMol Chemicals Inc. | ||
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2024-11-06 | diABZI STING agonist-1 (Tautomerism)
2138498-18-5
|
US $168.00-502.00 / mg | 99.72% | 10g | TargetMol Chemicals Inc. |
-
- diABZI STING agonist-1 (Tautomerism)
2138498-18-5
- US $168.00-502.00 / mg
- 99.72%
- TargetMol Chemicals Inc.
-
- diABZI STING agonist-1 (Tautomerism)
2138498-18-5
- US $168.00-502.00 / mg
- 99.72%
- TargetMol Chemicals Inc.
diABZI STING agonist-1 Tautomerism
1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[(2E)-5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-[3-(4-morpholinyl)propoxy]-, (2E)-
diABZI STING agonist 1 (compound 3)
diABZI STING agonist (Compound 3)
Tautomerism
(E)-1-((E)-4-((E)-5-Carbamoyl-2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-7-(3-morpholinopropoxy)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-7-methoxy-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide
2138498-18-5