PHENMETRAZINE HYDROCHLORIDE CII (200 MG)
- CAS No.
- 1707-14-8
- Chemical Name:
- PHENMETRAZINE HYDROCHLORIDE CII (200 MG)
- Synonyms
- marsin;C07433;Mefolin;Preludin;neo-zine;Usaf Ge-1;MFCD00242655;Preludin (TN);a66hydrochloride;preludinhydrochloride
- CBNumber:
- CB8501396
- Molecular Formula:
- C11H15NO.ClH
- Molecular Weight:
- 213.704
- MDL Number:
- MOL File:
- 1707-14-8.mol
| Melting point | 175-177°C |
|---|---|
| storage temp. | Controlled Substance, -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
| EWG's Food Scores | 1 |
| FDA UNII | 6U85YRT588 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
| RIDADR | 3249 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
PHENMETRAZINE HYDROCHLORIDE CII (200 MG) Chemical Properties,Uses,Production
Chemical Properties
White Solid
Originator
Preludin, Boehringer Ingelheim, US ,1956
Uses
Anorexic. Controlled substance (stimulant).
Definition
ChEBI: Phenmetrazine hydrochloride is an organic molecular entity.
Manufacturing Process
10 grams of β-phenyl-α-methyl-β,β'-dihydroxy-diethylamine hydrochloride (produced by hydrogenation in the presence of palladium and charcoal of βphenyl-α-methyl-β-keto-β'-hydroxy-N-benzyl-diethylamine hydrochloride obtained from bromopropiophenone by reacting with benzyl-ethanolamine), are warmed with 10% hydrochloric acid for 6 hours on a water bath.After working up in the usual manner, the hydrochloride of the 2-phenyl-3methyl-morpholine crystallizes out from methanolic hydrochloric acid and acetone, MP = 182°C, according to US Patent 2,835,669.
brand name
Preludin (Boehringer Ingelheim).
Therapeutic Function
Antiobesity
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human reproductive effects. Human teratogenic effects by ingestion: developmental abnormalities of the respiratory and gastrointestinal systems, and effects on newborn including neonatal measures or effects. When heated to decomposition it emits very toxic fumes of NOx and HCl.