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FLT3-IN-4

FLT3-IN-4 Structure
FLT3-IN-4 structure
CAS No.
2304799-09-3
Chemical Name:
FLT3-IN-4
Synonyms
FLT3-IN-4;1-{4-[4-amino-7-(prop-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl}-3-(5-tert-butyl-1,2-oxazol-3-yl)urea;Urea, N-[4-[4-amino-7-(2-propen-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]-N'-[5-(1,1-dimethylethyl)-3-isoxazolyl]-
CBNumber:
CB85540578
Molecular Formula:
C23H25N7O2
Molecular Weight:
431.49
MDL Number:
MFCD32067953
MOL File:
2304799-09-3.mol
Last updated:2024-11-19 20:33:22
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FLT3-IN-4 Properties

Boiling point 589.1±50.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 12.68±0.70(Predicted)
form Solid
color White to off-white

FLT3-IN-4 Chemical Properties,Uses,Production

Description

FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia[1].

FLT3-IN-4 (Compound 9u) shows potent inhibitory activities against MV4-11 and Molm-13 cells with IC50 values are 0.089±0.001 nM and 0.022±0.003 nM, respectively[1].

References

[1]. Yuan X, et al. Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia. J Med Chem. 2019 Apr 25;62(8):4158-4173.

FLT3-IN-4 Preparation Products And Raw materials

Raw materials

Preparation Products

FLT3-IN-4 Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4575 55
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2986 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4013 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29979 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9266 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai Rechem science Co., Ltd. 58
ShangHai ChuanQian Chemcial Technique Centre 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
https://hanhongsci.com/ 58
RD International Technology Co., Limited 58

View Lastest Price from FLT3-IN-4 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FLT3-IN-4 pictures 2024-11-19 FLT3-IN-4
2304799-09-3
 US $94.00-353.00 / mg 98.96% 10g TargetMol Chemicals Inc.
FLT3-IN-4 pictures 2024-11-19 FLT3-IN-4
2304799-09-3
 US $94.00-353.00 / mg 98.96% 10g TargetMol Chemicals Inc.
  • FLT3-IN-4 pictures
  • FLT3-IN-4
    2304799-09-3
  • US $94.00-353.00 / mg
  • 98.96%
  • TargetMol Chemicals Inc.
  • FLT3-IN-4 pictures
  • FLT3-IN-4
    2304799-09-3
  • US $94.00-353.00 / mg
  • 98.96%
  • TargetMol Chemicals Inc.

FLT3-IN-4 Spectrum

FLT3-IN-4(2304799-09-3)1HNMR
FLT3-IN-4 Urea, N-[4-[4-amino-7-(2-propen-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]-N'-[5-(1,1-dimethylethyl)-3-isoxazolyl]- 1-{4-[4-amino-7-(prop-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl}-3-(5-tert-butyl-1,2-oxazol-3-yl)urea 2304799-09-3