ChemicalBook >> CAS DataBase List >>SMARt-420
SMARt-420
- CAS No.
- 1616242-21-7
- Chemical Name:
- SMARt-420
- Synonyms
- BDM41420;SMARt-420;SMARt-420 (BDM41420);SMARt-420 >=98% (HPLC);1-Butanone, 4,4,4-trifluoro-1-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)-
- CBNumber:
- CB85867378
- Molecular Formula:
- C17H19F3N2O2
- Molecular Weight:
- 340.34
- MDL Number:
- MFCD31697724
- MOL File:
- 1616242-21-7.mol
Last updated:2025-01-27 09:38:02
SMARt-420 Chemical Properties,Uses,Production
Biological Activity
SMARt-420 (Small Molecule Aborting Resistance) activates an alternative bioactivation pathway of the tuberculosis antibiotic pro-drug ethionamide. Ethionamide bioactivation is normally catalyzed by monooxygenase EthA, but mutations in the enzyme have allowed many strains to become resistant. SMARt-420 activates a previously unknown pathway, reversing ethionamide-acquired resistance and clearing ethionamide-resistant infection in mice in addition to increasing the sensitivity of bacteria to ethionamide.
SMARt-420 Preparation Products And Raw materials
Raw materials
Preparation Products
SMARt-420 Suppliers
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44807 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8617 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12000 | 58 |
SMARt-420
SMARt-420 >=98% (HPLC)
1-Butanone, 4,4,4-trifluoro-1-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)-
SMARt-420 (BDM41420)
BDM41420
1616242-21-7