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Norhyodeoxycholic Acid

CAS No.
77518-23-1
Chemical Name:
Norhyodeoxycholic Acid
Synonyms
Norhyodeoxycholic Acid;(5β)-3α,6α-dihydroxy-24-norcholan-23-oic acid;24-Norcholan-23-oic acid, 3,6-dihydroxy-, (3α,5β,6α)-
CBNumber:
CB86198088
Molecular Formula:
C23H38O4
Molecular Weight:
378.55
MDL Number:
MOL File:
77518-23-1.mol
Last updated:2024-10-23 13:36:13

Norhyodeoxycholic Acid Properties

Melting point 197-198 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling point 536.7±25.0 °C(Predicted)
Density 1.142±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:1): 0.5mg/mL; DMSO: 20mg/mL; Ethanol: 20mg/mL
form A crystalline solid
pka 4.71±0.10(Predicted)

Norhyodeoxycholic Acid Chemical Properties,Uses,Production

Description

Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid (HDCA; ).1,2 NHDCA is an intermediate in the synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholen-23-oic acid, which has been used as an internal standard for the quantification of Δ5-bile acid conjugates that have been identified in patients with Niemann-Pick disease type C1.3

Definition

ChEBI: Norhyodeoxycholic acid is a cholanoid.

References

1. Schteingart, C.D., and Hofmann, A.F. Synthesis of 24-nor-5β-cholan-23-oic acid derivatives: A convenient and efficient one-carbon degradation of the side chain of natural bile acids J. Lipid Res. 29(10),1387-1395(1988).
2. Une, M., and Hoshita, T. Natural occurrence and chemical synthesis of bile alcohols, higher bile acids, and short side chain bile acids Hiroshima J. Med. Sci. 43(2),37-67(1994).
3. Kakiyama, G., Muto, A., Shimada, M., et al. Chemical synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholenoic acid: An internal standard for mass spectrometric analysis of the abnormal Δ5-bile acids occurring in Niemann-Pick disease Steroids 74(9),766-772(2009).

Norhyodeoxycholic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

Norhyodeoxycholic Acid Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Hubei Aiputi Bioengineering Co., Ltd. 17762444226 d17762444226@163.com China 2402 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19703 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12065 58

View Lastest Price from Norhyodeoxycholic Acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Norhyodeoxycholic Acid pictures 2024-10-24 Norhyodeoxycholic Acid
77518-23-1
US $293.00-1300.00 / mg 10g TargetMol Chemicals Inc.
Norhyodeoxycholic Acid 24-Norcholan-23-oic acid, 3,6-dihydroxy-, (3α,5β,6α)- (5β)-3α,6α-dihydroxy-24-norcholan-23-oic acid 77518-23-1