MELPERONE
- CAS No.
- Chemical Name:
- MELPERONE
- Synonyms
- MELPERONE;Methylperone
- CBNumber:
- CB8647243
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
FDA UNII | J8WA3K39B7 |
---|---|
ATC code | N05AD03 |
MELPERONE Chemical Properties,Uses,Production
Originator
Eunerpan,Nordmark,W. Germany,1965
Manufacturing Process
A solution or dispersion consisting of 20.1 g (0.1 mol) of γ-chloro-pfluorobutyrophenone, 19.8 g (0.2 mol) of 4-methylpiperidine and 0.1 g of potassium iodide in 150 ml toluene is heated in a sealed glass tube for 15 hours at 100°C to 110°C. The potassium iodide and the 4-methylpiperidine hydrochloride formed in the reaction are separated by filtration and the solvent removed from the filtrate by evaporation in vacuum on a steam bath. The residue is distilled and the fraction obtained at 120°C to 125°C and at a pressure lower than 0.1 mm Hg is collected. The base is dissolved in ether and the 4-fluoro-γ-(4-methylpiperidino)-butyrophenone precipitated as the hydrochloride. The reaction product is purified by recrystallization in ethanol/ether.
Yield 22.0 g (73% of theory). MP 209°C to 211°C.
Therapeutic Function
Neuroleptic
MELPERONE Preparation Products And Raw materials
MELPERONE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
United States Biological | -- | chemicals@usbio.net | United States | 6256 | 80 |
Shanghai Ziqi Biological Technology Co., Ltd. | -- | 2453006496@qq.com | CHINA | 6192 | 58 |
Guangzhou Weijia Technology Co., Ltd. | -- | WHIGA22@126.COM | CHINA | 6748 | 58 |
Beijing Fubo Biotechnology Co., Ltd. | -- | info@f-biology.com | CHINA | 6039 | 58 |
Shanghai Zhenyu Biological Technology Co., Ltd. | -- | 2836767067@qq.com | CHINA | 6970 | 58 |
Xiamen Research Biotechnology Co., Ltd. | -- | 1562893815@qq.com | CHINA | 6942 | 58 |
Shanghai Hao Biological Technology Co., Ltd. | -- | shxiyuanbio@163.com | CHINA | 6921 | 58 |
Shanghai Hao Zhun Biological Technology Co., Ltd. | -- | info@zzsrm.com | CHINA | 6846 | 58 |
Lanospharma Laboratories Co.,Ltd | -- | sales@lanospharma.com | China | 6343 | 56 |