Clobetasol
- CAS No.
- 25122-41-2
- Chemical Name:
- Clobetasol
- Synonyms
- CLOBETASOLE PROPIONATE;CLOBETASOL-17-PROPIONATE;Clobetasol;ClobetasolBase;Clobetasol USP/EP/BP;Clobetasol Impurity G;CLOBESTASOL PROPIONATE;Betamethasone Impurity B;BETAMETHASONE EP MPURITY B;Clobetasol impurity G (PhEur)
- CBNumber:
- CB8715108
- Molecular Formula:
- C22H28ClFO4
- Molecular Weight:
- 410.91
- MDL Number:
- MFCD03695616
- MOL File:
- 25122-41-2.mol
Melting point | 220-222°C |
---|---|
Boiling point | 555.1±50.0 °C(Predicted) |
Density | 1.32±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | Acetone (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 12.03±0.70(Predicted) |
color | White to Light Brown |
FDA UNII | ADN79D536H |
ATC code | D07AD01 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H360Df-H373-H413 |
Precautionary statements | P201-P308+P313 |
Hazard Codes | T |
Risk Statements | 61-48/20/21-53-62 |
Safety Statements | 53-36/37-45 |
Clobetasol price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | C583490 | Clobetasol | 25122-41-2 | 100mg | $1210 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024630 | CLOBETASOL 95.00% | 25122-41-2 | 100MG | $1758.49 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 68820 | Clobetasol | 25122-41-2 | 100mg | $2000 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 68820 | Clobetasol | 25122-41-2 | 10mg | $625 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024630 | CLOBETASOL 95.00% | 25122-41-2 | 10MG | $697.34 | 2021-12-16 | Buy |
Clobetasol Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Solid
Originator
Dermovate,Glaxo,UK,1973
Uses
Atorvastatin Intermediate
Uses
Clobetasol (Clobetasol Propionate EP Impurity G) is a topical corticosteroid. Glucocorticoid; anti-inflammatory.
Definition
ChEBI: A 3-oxo-Delta1,Delta4-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha posit ons, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.
Manufacturing Process
A solution of betamethasone 21-methanesulfonate (4 g) in dimethylformamide
(25 ml) was treated with lithium chloride (4 g) and the mixture heated on the
steam bath for 30 minutes. Dilution with water gave the crude product which
was recrystallized to afford the title compound, MP 226°C.
Clobetasol is usually converted to the propionate as the useful form by
reaction with propionic anhydride.
brand name
Clobex (Galderma); Clobex (Galderma); Embeline (Healthpoint); Olux (Connetics); Temovate (Altana).
Therapeutic Function
Corticosteroid, Antiinflammatory
Clobetasol Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14335 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49403 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29820 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7726 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15370 | 58 |
View Lastest Price from Clobetasol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-17 | Clobetasol
25122-41-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | ||
2024-09-20 | Betamethasone EP Impurity B
25122-41-2
|
US $0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | ||
2024-09-20 | Betamethasone EP Impurity B
25122-41-2
|
US $0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD |
- Clobetasol
25122-41-2
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
- Betamethasone EP Impurity B
25122-41-2
- US $0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
- Betamethasone EP Impurity B
25122-41-2
- US $0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
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