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Methyl 2-chloroacetoacetate

CAS No.
4755-81-1
Chemical Name:
Methyl 2-chloroacetoacetate
Synonyms
Methyl 2-chloro-3-oxobutanoate;Apixaban Impurity 210;2-chloro acetylacetate;METHYL 2-CHLOROACETOACETATE;Methyle2-chloroacetoacetate;METHYL 2-CHLORO-3-OXOBUTANATE;Methyl 2-chloroacetoacetate,95%;Methyl 2-Chloroacetoacetate >methyl alpha-chloroacetoacetate;Chloroacetoaceticacidmethylester
CBNumber:
CB8737542
Molecular Formula:
C5H7ClO3
Molecular Weight:
150.56
MDL Number:
MFCD00008757
MOL File:
4755-81-1.mol
Last updated:2024-08-17 21:30:02

Methyl 2-chloroacetoacetate Properties

Melting point -33--32.7 °C (lit.)
Boiling point 137 °C (lit.)
Density 1.236 g/mL at 25 °C (lit.)
refractive index n20/D 1.446(lit.)
Flash point 161 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Liquid
pka 7.89±0.46(Predicted)
color Clear yellow
Water Solubility 50 g/L (20 ºC)
CAS DataBase Reference 4755-81-1(CAS DataBase Reference)
FDA UNII 09T3687932
NIST Chemistry Reference Butanoic acid, 2-chloro-3-oxo-, methyl ester(4755-81-1)
EPA Substance Registry System Methyl 2-chloroacetoacetate (4755-81-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38-22
Safety Statements  26-27-28-36/37/39-37/39
RIDADR  UN 2810 6.1/PG 3
WGK Germany  3
HazardClass  8
PackingGroup  III
HS Code  29183000
NFPA 704
2
2 0

Methyl 2-chloroacetoacetate price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 183911 Methyl 2-chloroacetoacetate 4755-81-1 25g $198 2023-06-20 Buy
TCI Chemical C1219 Methyl 2-Chloroacetoacetate >95.0%(GC) 4755-81-1 25g $75 2024-03-01 Buy
TCI Chemical C1219 Methyl 2-Chloroacetoacetate >95.0%(GC) 4755-81-1 250g $444 2024-03-01 Buy
TRC M295562 Methyl 2-chloroacetoacetate 4755-81-1 25g $165 2021-12-16 Buy
TRC M295562 Methyl 2-chloroacetoacetate 4755-81-1 5g $55 2021-12-16 Buy
Product number Packaging Price Buy
183911 25g $198 Buy
C1219 25g $75 Buy
C1219 250g $444 Buy
M295562 25g $165 Buy
M295562 5g $55 Buy

Methyl 2-chloroacetoacetate Chemical Properties,Uses,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

Methyl 2-chloroacetoacetate was used in one-pot synthesis of 2-arylimidazole-4-carboxylic acids. It was also used in synthesis of 3,5-disubstituted 1,2,4-triazoles.

Synthesis Reference(s)

Synthesis, p. 188, 1987 DOI: 10.1055/s-1987-27886

Methyl 2-chloroacetoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 156)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3002 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5892 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18777 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58

View Lastest Price from Methyl 2-chloroacetoacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 2-Chloroacetoacetate pictures 2024-10-11 Methyl 2-Chloroacetoacetate
4755-81-1
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Methyl 2-Chloroacetoacetate pictures 2024-08-17 Methyl 2-Chloroacetoacetate
4755-81-1
US $1.00-1.50 / KG 1KG 99% 100000KG Shaanxi Dideu Medichem Co. Ltd
Methyl 2-chloroacetoacetate pictures 2021-07-02 Methyl 2-chloroacetoacetate
4755-81-1
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2-chloro-3-oxo-butanoicacimethylester Chloroacetoaceticacidmethylester Butanoic acid, 2-chloro-3-oxo-, methyl ester 2-chloro-3-oxo-butyric acid methyl ester 2-Acetyl-2-chloroacetic acid methyl ester Methyl 2-chloroacetoacetate,95% 2-chloro acetylacetate 2-CHLOROACETOACETIC ACID METHYL ESTER 2-chloro-3-oxobutanoic acid, methyl ester METHYL 2-CHLORO-3-OXOBUTANATE METHYL 2-CHLOROACETOACETATE Methyle2-chloroacetoacetate (2S)-2-chloro-3-oxobutanoic acid methyl ester Methyl 2-Chloroacetoacetate > Apixaban Impurity 210 Methyl 2-chloro-3-oxobutanoate methyl alpha-chloroacetoacetate 4755-81-1 4775-81-1 CH3COCHClCO2CH3 Building Blocks Carbonyl Compounds C2 to C5 Organic Building Blocks Esters Building Blocks C2 to C5 Carbonyl Compounds Chemical Synthesis Organic Building Blocks C2 to C5 Carbonyl Compounds Esters