ChemicalBook >> CAS DataBase List >>Methyl coumalate
Methyl coumalate
- CAS No.
- 6018-41-3
- Chemical Name:
- Methyl coumalate
- Synonyms
- METHYL 2-OXO-2H-PYRAN-5-CARBOXYLATE;Coumalic acid methyl ester;Methyl coumaric acid;METHYL COUMALATE;TIMTEC-BB SBB000117;Methyl coumalate 98%;Methyl Coumalate >5-(Carbomethoxy)-2-pyrone;Methyl 2-pyrone-5-carboxylate;METHYL PYR-2-ONE-5-CARBOXYLATE
- CBNumber:
- CB8755382
- Molecular Formula:
- C7H6O4
- Molecular Weight:
- 154.12
- MDL Number:
- MFCD00010120
- MOL File:
- 6018-41-3.mol
- MSDS File:
- SDS
Last updated:2025-02-12 20:55:48
| Melting point | 65-67 °C (lit.) |
|---|---|
| Boiling point | 178-180 °C/60 mmHg (lit.) |
| Density | 1.1993 (rough estimate) |
| refractive index | 1.4300 (estimate) |
| Flash point | 178-180°C/60mm |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Freely soluble in dichloromethane. |
| form | powder to crystal |
| color | White to Orange to Green |
| Merck | 14,2557 |
| BRN | 126301 |
| LogP | -0.660 (est) |
| CAS DataBase Reference | 6018-41-3(CAS DataBase Reference) |
| FDA UNII | 1S7TMF0R8T |
| NIST Chemistry Reference | 2H-Pyran-5-carboxylic acid, 2-oxo-, methyl ester(6018-41-3) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H334-H351b | |||||||||
| Precautionary statements | P201-P202-P261-P272-P280g-P302+P352-P308+P313-P363-P403-P501c | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2932209090 | |||||||||
| NFPA 704 |
|
Methyl coumalate price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 261432 | Methyl coumalate 98% | 6018-41-3 | 10g | $441 | 2024-03-01 | Buy |
| TCI Chemical | C1734 | Methyl Coumalate >96.0%(GC) | 6018-41-3 | 5g | $85 | 2024-03-01 | Buy |
| TCI Chemical | C1734 | Methyl Coumalate >96.0%(GC) | 6018-41-3 | 25g | $278 | 2024-03-01 | Buy |
| Alfa Aesar | B25330 | Methyl coumalate, 98% | 6018-41-3 | 2g | $47.65 | 2024-03-01 | Buy |
| Alfa Aesar | B25330 | Methyl coumalate, 98% | 6018-41-3 | 10g | $165.65 | 2024-03-01 | Buy |
Methyl coumalate Chemical Properties,Uses,Production
Uses
α, β-Unsaturated ketone Methyl Coumalate showed cytotoxicity against human normal gingival fibroblast cells and oral squamous cell carcinoma cell line-2.
Uses
Methyl coumalate has been used as reagent in phosphine-catalyzed [4+3] annulation of modified allylic carbonates. It was also used in the preparation of 7-carboxyquinolizinium derivatives.
Uses
Methyl coumalate is a 2-pyrone and acts as dienophile in Diels-Alder reaction. It reacts with 1,3-butadienes at 100°C to yield tetrahydrocoumarins and 4-methoxycarbonyltricyclo[3.2.1.02,7]octenes. It also reacts with cyclohexadiene to afford tetrahydronaphthalene-2-carboxylate. It undergoes Diels-Alder reaction with unactivated alkenes to afford para-substituted adducts. It has been used as reagent in phosphine-catalyzed [4+3] annulation of modified allylic carbonates. It was also used in the preparation of 7-carboxyquinolizinium derivatives.
General Description
Methyl coumalate is a 2-pyrone and acts as dienophile in Diels-Alder reaction. It reacts with 1,3-butadienes at 100°C to yield tetrahydrocoumarins and 4-methoxycarbonyltricyclo[3.2.1.02,7]octenes. It also reacts with cyclohexadiene to afford tetrahydronaphthalene-2-carboxylate. It undergoes Diels-Alder reaction with unactivated alkenes to afford para-substituted adducts.
Methyl coumalate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 187)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 3712 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 19918 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49476 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29809 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7724 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15352 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9310 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
View Lastest Price from Methyl coumalate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-18 | Methyl coumalate
6018-41-3
|
US $50.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2025-02-13 | Methyl Coumalate
6018-41-3
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2023-05-04 | Methyl coumaric acid
6018-41-3
|
US $48.00-40.00 / KG | 1KG | 99% | 200tons | Guangzhou Sunton Biotechnology Co., Ltd. |
-
- Methyl coumalate
6018-41-3
- US $50.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- Methyl Coumalate
6018-41-3
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- Methyl coumaric acid
6018-41-3
- US $48.00-40.00 / KG
- 99%
- Guangzhou Sunton Biotechnology Co., Ltd.
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6018-41-3
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