Sodium hydroxymethanesulphinate
- CAS No.
- 149-44-0
- Chemical Name:
- Sodium hydroxymethanesulphinate
- Synonyms
- RONGALITE;SODIUM FORMALDEHYDE SULFOXYLATE;SODIUM HYDROXYMETHANESULFINATE;RONGALITE C;SODIUM FORMALDEHYDESULFOXALATE;Natriumhydroxymethansulfinat;Sodiumbisulfoxylateformaldehyde;Sodium hydroxymethanesulfinate hydrate;HYDROXYMETHANESULFINIC ACID SODIUM SALT;aldanil
- CBNumber:
- CB8773339
- Molecular Formula:
- CH3NaO3S
- Molecular Weight:
- 118.09
- MDL Number:
- MFCD00040426
- MOL File:
- 149-44-0.mol
- MSDS File:
- SDS
| Melting point | ~120 °C (dec.) |
|---|---|
| Density | 1.744[at 20℃] |
| vapor pressure | 0.003Pa at 20℃ |
| Flash point | >100℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 50 mg/mL, clear, colorless |
| form | Solid |
| color | White to Off-White |
| PH | 9.5-10.5 |
| Water Solubility | soluble H2O, alcohol [HAW93] |
| Merck | 14,8620 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| LogP | -3.4 at 22℃ |
| Indirect Additives used in Food Contact Substances | SODIUM FORMALDEHYDESULFOXYLATE |
| FDA 21 CFR | 175.105; 176.170; 177.1210; 177.2600 |
| FDA UNII | X4ZGP7K714 |
| EPA Substance Registry System | Sodium sulfoxylate formaldehyde (anhydrous) (149-44-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H341-H315-H319-H335 | |||||||||
| Precautionary statements | P280-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-68-31 | |||||||||
| Safety Statements | 26-36-36/37 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | PB0380000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2930909899 | |||||||||
| NFPA 704 |
|
Sodium hydroxymethanesulphinate price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | R0053 | Sodium Hydroxymethanesulfinate Dihydrate >97.0%(T) | 149-44-0 | 500g | $28 | 2022-04-27 | Buy |
| Alfa Aesar | A15731 | Hydroxymethanesulfinic acid sodium salt hydrate, tech 85%, cont. up to 5% sodium sulfite (dry wt.) | 149-44-0 | 500g | $30.65 | 2024-03-01 | Buy |
| Alfa Aesar | A15731 | Hydroxymethanesulfinic acid sodium salt hydrate, tech 85%, cont. up to 5% sodium sulfite (dry wt.) | 149-44-0 | 2500g | $118.65 | 2024-03-01 | Buy |
| TRC | S634953 | Sodium hydroxymethanesulfinate hydrate | 149-44-0 | 10g | $135 | 2021-12-16 | Buy |
| Usbiological | 279673 | Sodium hydroxymethanesulfinate hydrate | 149-44-0 | 250g | $319 | 2021-12-16 | Buy |
Sodium hydroxymethanesulphinate Chemical Properties,Uses,Production
Chemical Properties
When freshly prepared, sodium formaldehyde sulfoxylate occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.
Chemical Properties
white solid; used as stripping and discharge agent for textiles [HAW93]
Uses
Sodium Hydroxymethanesulfinate Hydrate is the hydrated version of Sodium Hydroxymethanesulfinate (S634950), which is an organic reductant that is stable in alkaline enviroments but readily decomposes in acidic medium to produce a number of products, one of them being sulfur dioxide. Sodium hydroxymethanesulfinate is also used in conjunction with substituted anilines (e.g. p-Anisidine [A673505]) to synthesize anilinomethanesulfonates.
Uses
Pharmaceutic aid (preservative).
Production Methods
Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.
Flammability and Explosibility
Non flammable
Pharmaceutical Applications
Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.
Safety
The toxicological properties of sodium formaldehyde sulfoxylate
have not been fully investigated. However, it is used in the
formulation of injection products at a level to 0.1% w/v in the
final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by
ingestion, and when heated to decomposition it emits toxic fumes
of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg
storage
Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).
Purification Methods
It crystallises from H2O as the dihydrate and decomposes at higher temperatures. Store it in a closed container in a cool place. It is insoluble in EtOH and Et2O and is a good reducing agent. [X-ray structure: Tuter J Chem Soc 3064 1955.] Note that this compound {HOCH2SO2Na} should not be confused with formaldehyde sodium bisulfite adduct {HOCH2SO3Na} from which it is prepared by reduction with Zn. [Beilstein 1 IV 3052.]
Incompatibilities
Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.
Regulatory Status
Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Sodium hydroxymethanesulphinate Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12841 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20285 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 | admin@hbsaisier.cn | China | 1015 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
View Lastest Price from Sodium hydroxymethanesulphinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-29 | Sodium hydroxymethanesulphinate
149-44-0
|
US $6.00 / kg | 1kg | More than 99% | 2000KG/Month | Hebei Longbang Technology Co., Ltd | |
 |
2024-11-29 | Sodium hydroxymethanesulphinate
149-44-0
|
US $6.00 / kg | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | |
 |
2024-11-29 | Sodium hydroxymethanesulphinate
149-44-0
|
US $70.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- Sodium hydroxymethanesulphinate
149-44-0
- US $6.00 / kg
- More than 99%
- Hebei Longbang Technology Co., Ltd
-
- Sodium hydroxymethanesulphinate
149-44-0
- US $6.00 / kg
- 99%
- HebeiShuoshengImportandExportco.,Ltd
-
- Sodium hydroxymethanesulphinate
149-44-0
- US $70.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co.,Ltd
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