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SGK1-IN-2

SGK1-IN-2 Structure
SGK1-IN-2 structure
CAS No.
1426214-64-3
Chemical Name:
SGK1-IN-2
Synonyms
SGK1-IN-2;Sanofi-14H;SGK1IN2,SGK1 IN 2,SGK-1-IN-2;Benzenesulfonamide, N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,5-dichloro-
CBNumber:
CB88054539
Molecular Formula:
C17H12Cl2N6O2S
Molecular Weight:
435.29
MDL Number:
MFCD32671325
MOL File:
1426214-64-3.mol
Last updated:2024-07-02 08:55:37
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SGK1-IN-2 Properties

Boiling point 726.0±70.0 °C(Predicted)
Density 1.660±0.06 g/cm3(Predicted)
solubility DMSO : 62.5 mg/mL (143.58 mM; Need ultrasonic)
form Solid
pka 5.86±0.10(Predicted)
color Light yellow to yellow

SGK1-IN-2 Chemical Properties,Uses,Production

Biological Activity

SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration[1].

References

[1]. Halland N, et al. Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors. ACS Med Chem Lett. 2014 Oct 23;6(1):73-8.

SGK1-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

SGK1-IN-2 Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 23963 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9268 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai EFE Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
RD International Technology Co., Limited 58
SGK1-IN-2 SGK1IN2,SGK1 IN 2,SGK-1-IN-2 Sanofi-14H Benzenesulfonamide, N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,5-dichloro- 1426214-64-3