6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2,2-dimethyl-4-oxo-3-phenyl-

6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2,2-dimethyl-4-oxo-3-phenyl- structure

CAS No.: 28638-47-3

Chemical Name:: 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2,2-dimethyl-4-oxo-3-phenyl-

Synonyms: 2,2-Dimethyl Metolazone;Metolazone Dimethyl Impurity;6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2,2-dimethyl-4-oxo-3-phenyl-

CBNumber:: CB88187886

Molecular Formula:: C16H16ClN3O3S

Molecular Weight:: 365.83

MDL Number:

MOL File:: 28638-47-3.mol

Last updated:2023-04-23 13:52:06

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6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2,2-dimethyl-4-oxo-3-phenyl- Properties

Melting point	>125oC (dec.)
Boiling point	600.5±65.0 °C(Predicted)
Density	1.389±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	10.03±0.60(Predicted)
color	Pale Brown

6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2,2-dimethyl-4-oxo-3-phenyl- Chemical Properties,Uses,Production

Uses

2,2-Dimethyl Metolazone is an intermediate used in the synthesis of Desmethyl Metolazone (D292450), which is an impurity of Metolazone (M338750); a diuretic and antihypertensivent agent.

6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2,2-dimethyl-4-oxo-3-phenyl- Preparation Products And Raw materials

Raw materials

Preparation Products

6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2,2-dimethyl-4-oxo-3-phenyl- Metolazone Dimethyl Impurity 2,2-Dimethyl Metolazone 28638-47-3