6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydimethylsilyl)-2-methylene-3-[(phenylmethoxy)methyl]cyclopentyl]-

CAS No.
701278-12-8
Chemical Name:
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydimethylsilyl)-2-methylene-3-[(phenylmethoxy)methyl]cyclopentyl]-
Synonyms
Methylphenyl Entecavir DimethylhydroxySilane;6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydimethylsilyl)-2-methylene-3-[(phenylmethoxy)methyl]cyclopentyl]-
CBNumber:
CB88327790
Molecular Formula:
C21H27N5O3Si
Molecular Weight:
425.56
MDL Number:
MOL File:
701278-12-8.mol

6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydimethylsilyl)-2-methylene-3-[(phenylmethoxy)methyl]cyclopentyl]- Properties

Boiling point 651.8±65.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
pka 14.65±0.60(Predicted)

6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydimethylsilyl)-2-methylene-3-[(phenylmethoxy)methyl]cyclopentyl]- Chemical Properties,Uses,Production

Uses

Methylphenyl Entecavir DimethylhydroxySilane is used in the preparation of the the antiviral agent Entecavir (E558900).

6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydimethylsilyl)-2-methylene-3-[(phenylmethoxy)methyl]cyclopentyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydimethylsilyl)-2-methylene-3-[(phenylmethoxy)methyl]cyclopentyl]- Methylphenyl Entecavir DimethylhydroxySilane 701278-12-8 C21H27N5O3Si