ChemicalBook >> CAS DataBase List >>3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID

CAS No.
227619-65-0
Chemical Name:
3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID
Synonyms
HIP-B;(±)HIPB,(±) HIP B;3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID;rel-(3aR,6R,6aR)-Hexahydro-3-oxo-2H-pyrrolo[3,4-d]isoxazole-6-carboxylic acid;2H-Pyrrolo[3,4-d]isoxazole-6-carboxylic acid, hexahydro-3-oxo-, (3aR,6R,6aR)-rel-
CBNumber:
CB8839808
Molecular Formula:
C6H8N2O4
Molecular Weight:
172.14
MDL Number:
MFCD08703103
MOL File:
227619-65-0.mol
Last updated:2023-05-18 11:31:08

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Properties

storage temp. Store at +4°C
form Powder
Water Solubility Soluble to 20 mM in water

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology B6983 (±)-HIP-B 227619-65-0 10mg $322 2021-12-16 Buy
American Custom Chemicals Corporation CHM0370816 3-HYDROXY-4,5,6,6ALPHA-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID 95.00% 227619-65-0 5MG $495.21 2021-12-16 Buy
Product number Packaging Price Buy
B6983 10mg $322 Buy
CHM0370816 5MG $495.21 Buy

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Chemical Properties,Uses,Production

Uses

HIP-B is a potent, non-competitive excitatory amino acid transporter (EAAT) blocker. It can also be used as AMPA-Kainate receptor agonists.

Biological Activity

Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [ 3 H]D-aspartate release (IC 50 = 1.2 μ M) rather than [ 3 H]L-glutamate uptake (IC 50 = 16.9 μ M). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC 50 values are 35 and 45 μ M respectively).

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19689 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
United States Biological -- sales@advtechind.com United States 6075 58
ApexBio Technology -- sales@apexbt.com United States 6251 58

227619-65-0(3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID)Related Search:

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID HIP-B 2H-Pyrrolo[3,4-d]isoxazole-6-carboxylic acid, hexahydro-3-oxo-, (3aR,6R,6aR)-rel- rel-(3aR,6R,6aR)-Hexahydro-3-oxo-2H-pyrrolo[3,4-d]isoxazole-6-carboxylic acid (±)HIPB,(±) HIP B 227619-65-0 Glutamate receptor