1,3,5-Trichlorobenzene

1,3,5-Trichlorobenzene Properties

Melting point	63 °C
Boiling point	208 °C(lit.)
Density	1.4528 (estimate)
vapor pressure	0.58 at 25 °C (quoted, Mackay et al., 1982)
refractive index	1.5693 (estimate)
Flash point	260 °F
storage temp.	0-6°C
solubility	Soluble in benzene, ether, ligroin (Weast, 1986), glacial acetic acid, carbon disulfide, and petroleum ether (Windholz et al., 1983)
form	powder or crystals
color	Off-White
Water Solubility	Insoluble in water.
Merck	14,9632
BRN	1635233
Henry's Law Constant	1.83, 2.04, 2.64, 4.49, and 5.24 at 2.0, 6.0, 10.0, 18.0, and 25.0 °C, respectively (EPICS-SPME, Dewulf et al., 1999)
Stability	Stable. Incompatible with acids, strong oxidizing agents.
LogP	4.190
CAS DataBase Reference	108-70-3(CAS DataBase Reference)
FDA UNII	2HS4M0BX3C
NIST Chemistry Reference	Benzene, 1,3,5-trichloro-(108-70-3)
EPA Substance Registry System	1,3,5-Trichlorobenzene (108-70-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335-H412

Precautionary statements

P261-P273-P280-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-36/37/38-38-22-52/53

Safety Statements

26-36-36/37-61

RIDADR

3077

WGK Germany

3

RTECS

DC2100100

Hazard Note

Harmful/Irritant

TSCA

Yes

HazardClass

9

PackingGroup

III

HS Code

29039990

Hazardous Substances Data

108-70-3(Hazardous Substances Data)

Toxicity

Drinking water standard: No MCLGs or MCLs have been proposed, however, a DWEL of 200 μg/L was recommended (U.S. EPA, 2000).

NFPA 704

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2		0

1,3,5-Trichlorobenzene price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T54607	1,3,5-Trichlorobenzene 99%	108-70-3	100g	$80.1	2024-03-01	Buy
Sigma-Aldrich	03824	1,3,5-Trichlorobenzene certified reference material, TraceCERT	108-70-3	100mg	$119	2024-03-01	Buy
Alfa Aesar	L02132	1,3,5-Trichlorobenzene, 98%	108-70-3	50g	$42.1	2023-06-20	Buy
Usbiological	411208	1,3,5-Trichlorobenzene	108-70-3	250mg	$403	2021-12-16	Buy
TRC	T773790	1,3,5-Trichlorobenzene	108-70-3	1g	$405	2021-12-16	Buy

Product number	Packaging	Price	Buy
T54607	100g	$80.1	Buy
03824	100mg	$119	Buy
L02132	50g	$42.1	Buy
411208	250mg	$403	Buy
T773790	1g	$405	Buy

1,3,5-Trichlorobenzene Chemical Properties,Uses,Production

Description

Trichlorobenzenes (TCBs) are synthetic chemicals that occur in three different isomeric forms. The three chlorinated cyclic aromatic isomers are 1,2,3-trichlorobenzene (1,2,3-TCB), 1,2,4-trichlorobenzene (1,2,4-TCB), and 1,3,5-trichlorobenzene (1,3,5-TCB). 1,2,4-TCB is one of the 188 chemicals designated as a hazardous air pollutant under the Clean Air Act.

Chemical Properties

white to beige crystalline powder

Uses

1,3,5-Trichlorobenzene is used for someof these applications plus as a termite preparation and insecticide. These compounds are found as unintended by-products of the manufacture of the mono- and dichlorobenzenes.

Uses

1,3,5-Trichlorobenzene is an isomer of 1,2,4-Trichlorobenzene (T774220) which is a solvent in various organic chemical reactions.

Uses

Trichlorobenzenes are primarily used as solvents in chemical manufacturing industries. 1,2,4-Trichlorobenzene is economically the most important isomer. 1,2,4-Trichlorobenzene is used as a solvent in chemical reactions to dissolve oils, waxes, and resins. Furthermore, it is also used as a dye carrier. 1,2,3- Trichlorobenzene is used as an intermediate for pesticides production, pigments, and dyes. 1,3,5-Trichlorobenzene is not marketed commercially and has very limited use as a chemical intermediate. Besides, trichlorobenzenes can also be used as degreasing agents, as septic tanks and drain cleaners, and as an ingredient in wood preservatives and abrasive formulations. Other minor uses include metal work, anticorrosive paint, and corrosion inhibitor in sprays. In the past, mixed isomers of trichlorobenzenes were used to control termites; however, their use has been discontinued.

Definition

ChEBI: 1,3,5-trichlorobenzene is a trichlorobenzene carrying chloro substituents at positions 1, 3 and 5.

General Description

White to off-white crystals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Can react vigorously with oxidizing materials. .

Fire Hazard

1,3,5-Trichlorobenzene is combustible.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic vapors of Cl-.

Environmental Fate

Biological. Under aerobic conditions, soil microbes degraded 1,3,5-trichlorobenzene to 1,3- and 1,4-dichlorobenzene and carbon dioxide (Kobayashi and Rittman, 1982). A mixed culture of soil bacteria or a Pseudomonas sp. transformed 1,3,5-trichlorobenzene to 2,4,6-trichlorophenol (Ballschiter and Scholz, 1980).
In an enrichment culture derived from a contaminated site in Bayou d’Inde, LA, 1,3,5- trichlorobenzene underwent reductive dechlorination yielding 1,3-dichlorobenzene. The maximum dechlorination rate, based on the recommended Michaelis-Menten model, was 9.5 nM/d (Pavlostathis and Prytula, 2000).
Photolytic. The sunlight irradiation of 1,3,5-trichlorobenzene (20 g) in a 100-mL borosilicate glass-stoppered Erlenmeyer flask for 56 d yielded 160 ppm pentachlorobiphenyl (Uyeta et al., 1976). A photooxidation half-life of 6.17 months was reported for the vapor-phase reaction of 1,3,5-trichlorobenzene with OH radicals (Atkinson, 1985).

Purification Methods

Recrystallise it from dry *benzene or toluene. [Beilstein 5 IV 666.]

Toxicity evaluation

The liver is themain target of trichlorobenzenes irrespective of the route of exposure. The mechanisms of liver toxicity induced by these chemicals have not been illustrated. It might involve intermediate arene oxides formed during initial transformation to trichlorophenols. In addition, exposure to 1,2,4-TCB induced porphyria in rats by inducing daminolevulinic acid (ALA) synthetase, a rate-limiting enzyme in the biosynthesis of heme, and also heme oxygenase, a ratelimiting enzyme in the degradation of heme synthetase, and therefore increasing heme production.

1,3,5-Trichlorobenzene synthesis

Synthesis of 1,3,5-Trichlorobenzene from 1-Bromo-3,5-dichlorobenzene

1,3,5-Trichlorobenzene Preparation Products And Raw materials

Raw materials

2,4,6-Trichloroaniline 1,2,3-Trichlorobenzene 1,2,4-Trichlorobenzene ethyl 2-methoxyacrylate 1,3-Dibromo-5-chlorobenzene

2,2',4,4',6,6'-HEXACHLOROBIPHENYL 2,4,6-Trichloroiodobenzene PENTACHLOROBENZENE 1,2,3,5-Tetrachlorobenzene LINDANE

1-Bromo-3,5-dichlorobenzene

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Preparation Products

2,4,6-Trichlorobenzoic acid 1,2,3-Trichlorobenzene 1,2,4-Trichlorobenzene 3,5-Dichloroaniline 3',5'-DICHLORO-2,2,2-TRIFLUOROACETOPHENONE

3,5-Dichlorophenol

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1,3,5-Trichlorobenzene Suppliers

Global( 306)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Yancheng Green Chemicals Co.,Ltd	+undefined-86-25-86655873	info@royal-chem.com	China	114	58
Ningxia Jinhua Chemical Co.,Ltd	025-52279164	info@nxjhchem.com	China	79	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5889	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20283	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9026	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32956	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58

Supplier	Advantage
Yancheng Green Chemicals Co.,Ltd	58
Ningxia Jinhua Chemical Co.,Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58

View Lastest Price from 1,3,5-Trichlorobenzene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-12-26	1,3,5-Trichlorobenzene 108-70-3	US $0.00 / Kg/Drum	25Kg/Drum	99	1mt	Ningxia Jinhua Chemical Co.,Ltd
2024-12-26	1,3,5-Trichlorobenzene 108-70-3	US $0.00 / KG	25KG	99	1mt	Yancheng Green Chemicals Co.,Ltd
2024-12-26	1,3,5-Trichlorobenzene 108-70-3	US $0.00 / Kg/Drum	25Kg/Drum	99	1mt	Changde Changlian Chemical Co., Ltd.

1,3,5-Trichlorobenzene
108-70-3
US $0.00 / Kg/Drum
99
Ningxia Jinhua Chemical Co.,Ltd

1,3,5-Trichlorobenzene
108-70-3
US $0.00 / KG
99
Yancheng Green Chemicals Co.,Ltd

1,3,5-Trichlorobenzene
108-70-3
US $0.00 / Kg/Drum
99
Changde Changlian Chemical Co., Ltd.

1,3,5-Trichlorobenzene Spectrum

1,3,5-Trichlorobenzene(108-70-3)MS 1,3,5-Trichlorobenzene(108-70-3)¹HNMR 1,3,5-Trichlorobenzene(108-70-3)¹³CNMR 1,3,5-Trichlorobenzene(108-70-3)IR1 1,3,5-Trichlorobenzene(108-70-3)IR2 1,3,5-Trichlorobenzene(108-70-3)IR3 1,3,5-Trichlorobenzene(108-70-3)Raman

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1-Methoxy-2,4,6-trichlorobenzene HEXACHLOROBENZENE 1-Amino-2，4，6-trichlorobenzene 1,3,5-Trichloro-2,4,6-trifluorobenzene 2,3,4,6-TETRACHLOROPHENOL SODIUM SALT

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Benzene,1,3,5-trichloro- I,3,5-TrichlorbenzolVW,16 s-Trichlorobenzene trichloro-1,3,5benzene 1,3,5-TRICHLOROBENZENE PESTANAL, 250 MG 1 3 5-TRICHLOROBENZENE TECH. 90% 1,3,5-TRICHLOROBENZENE, 1000MG, NEAT 1,3,5-Trichlorbenzol 1,3,5-TRICHLOROBENZENE pure 1,3,5-Trichlorobenzene,99% 1,3,5-Trichlorobenzene 1.3.5-Trichlorobenzene 1g [108-70-3] 1,3,5-trichloro-benzen ai3-22031 SYM-TRICHLOROBENZENE 1,3,5-Trichlorobenze 1,3,5-Trichlorobenzene in Isooctane 1,3,5-Trichlorobenzene, 99.0%(GC) 1.3.5-Tric 1,3,5-TrichL 1,3,5-Trichlorobenzene 10 μg/mL in Cyclohexane 1,3,5-trichlorobenzeneSolution,100mg/L,1ml 1,3,5-TrichlorobenzeneSolution,10,000mg/L,5ml 1,3,5-Trichlorobenzene > 1,3,5-trichlorobenzeneSolution,1,000mg/L,1ml 1,3,5-TrichlorobenzeneSolution,10,000mg/L,1ml 1,3,5-Trichlorobenzene ISO 9001：2015 REACH 108-70-3 C6H3Cl3 1,3,5-Trichlorobenzene 1,3,5-Trichlorobenzene (1,3,5-TCB) pure, 99% Trichlorobenzene TCB 1,3,5-TCB Anagrelide Impurity 9 1,3,5-Trichlorobenzene Solution in Hexane 1,3,5-Trichlorobenzene Solution in Methylene chloride 1,3,5-Trichlorobenzene 10 μg/ml Acetonitrile 1,3,5-Trichlorobenzene 100 μg/ml Methanol C17723500 1,3,5-Trichlorobenzene 1.3.5-Trichlorobenzene in Methanol 1.3.5-Trichlorobenzene in n-Hexane 108-70-3 C6Cl3H3 C6H3CI3 108703 Building Blocks Aryl C6 Organic Building Blocks Halogenated Hydrocarbons Analytical Standards AromaticsChemical Class Chemical Class ChloroVolatiles/ Semivolatiles Halogenated TP - TZ T-ZAlphabetic Aryl C6