N-Methyl-D-aspartic acid
- CAS No.
- 6384-92-5
- Chemical Name:
- N-Methyl-D-aspartic acid
- Synonyms
- NMDA;n-methylaspartate;N-Me-D-Asp;H-D-MEASP-OH;N-ME-D-ASP-OH;H-D-MEASP-OH HCL;-D-aspartic acid;N-Methyl-D-Asp-OH;N-ME-D-ASP-OH HCL;n-methyl-d-aspartate
- CBNumber:
- CB8854056
- Molecular Formula:
- C5H9NO4
- Molecular Weight:
- 147.13
- MDL Number:
- MFCD00004226
- MOL File:
- 6384-92-5.mol
- MSDS File:
- SDS
Melting point | 187-192 °C |
---|---|
alpha | -28 º (c=1, HCl 6N) |
Boiling point | 267.21°C (rough estimate) |
Density | 1.4285 (rough estimate) |
refractive index | -15 ° (C=2, H2O) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly) |
form | solid |
pka | 2.21±0.23(Predicted) |
color | white |
Water Solubility | slightly soluble |
Sensitive | Hygroscopic |
Merck | 14,6662 |
BRN | 1724431 |
LogP | 1.390 (est) |
CAS DataBase Reference | 6384-92-5(CAS DataBase Reference) |
FDA UNII | 1903B9Q6PI |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() GHS07,GHS08,GHS09 |
---|---|
Signal word | Danger |
Hazard statements | H319-H400-H372 |
Precautionary statements | P273-P305+P351+P338 |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
RTECS | CI9457000 |
F | 10 |
HS Code | 29225090 |
N-Methyl-D-aspartic acid price More Price(52)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | M3262 | N-Methyl-D-aspartic acid ≥98% (TLC), solid | 6384-92-5 | 1g | $1040 | 2024-03-01 | Buy |
Sigma-Aldrich | 454575 | N-Methyl-D-aspartic Acid, Hydrate Excitatory amino acid neurotransmitter. | 6384-92-5 | 100mg | $322 | 2024-03-01 | Buy |
TCI Chemical | M1360 | N-Methyl-D-aspartic Acid >98.0%(T) | 6384-92-5 | 100mg | $22 | 2024-03-01 | Buy |
TCI Chemical | M1360 | N-Methyl-D-aspartic Acid >98.0%(T) | 6384-92-5 | 1g | $56 | 2024-03-01 | Buy |
Alfa Aesar | J61361 | N-Methyl-D-aspartic acid, 98+% | 6384-92-5 | 50mg | $75.65 | 2024-03-01 | Buy |
N-Methyl-D-aspartic acid Chemical Properties,Uses,Production
Chemical Properties
white to off-white crystalline powder
Uses
NMDA agonist
Uses
NMDA(N-Methyl-D-aspartic acid)is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.
Definition
ChEBI: An aspartic acid derivative having an N-methyl substituent and D-configuration.
General Description
N-Methyl-D-aspartic acid (NMDA) is an endogenously generated molecule in rat nervous system and endocrine glands. NMDA is present at low level (nmol/g) in the adenohypophysis, hypothalamus, brain, and testis. NMDA is derived from D-Asp by an S-adenosylmethionine-dependent enzyme also referred to as NMDA synthase.
Biological Activity
Prototypic NMDA receptor agonist. Also available as part of the Mixed NMDA Receptor Tocriset™ .
Biochem/physiol Actions
Excitotoxic amino acid. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy.
storage
Room temperature
References
[1] watkins jc, jane de. the glutamate story. br j pharmacol. 2006 jan;147 suppl 1:s100-8.
[2] lafon-cazal m, pietri s, culcasi m, bockaert j. nmda-dependent superoxide production and neurotoxicity. nature. 1993 aug 5;364(6437):535-7.
N-Methyl-D-aspartic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3320 | 58 |
Hebei Dangtong Import and export Co LTD | +8619831957301 | admin@hbdangtong.com | China | 983 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | daisy@enlaibio.com | China | 1106 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | sales@alabiochem.com | China | 888 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
View Lastest Price from N-Methyl-D-aspartic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-24 | N-Methyl-D-aspartic acid
6384-92-5
|
US $1.00-9.90 / g | 1g | 99% | 100kg | Wuhan Cell Pharmaceutical Co., Ltd | |
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2024-08-20 | N-Me-D-Asp
6384-92-5
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | |
![]() |
2024-08-06 | N-Methyl-D-aspartic acid
6384-92-5
|
US $3288.00-2680.00 / kg | 1kg | 99% | 1000kg | Hebei Dangtong Import and export Co LTD |
-
- N-Methyl-D-aspartic acid
6384-92-5
- US $1.00-9.90 / g
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd
-
- N-Me-D-Asp
6384-92-5
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- N-Methyl-D-aspartic acid
6384-92-5
- US $3288.00-2680.00 / kg
- 99%
- Hebei Dangtong Import and export Co LTD