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ChemicalBook >> CAS DataBase List >>Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]-

Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]-

Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]- Structure
Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]- structure
CAS No.
2597186-19-9
Chemical Name:
Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]-
Synonyms
SR0813,SR 0813;N-cyclobutyl-2-(3-((N-(2-(piperidin-1-yl)ethyl)sulfamoyl)amino)phenyl)imidazo[1,2-a]pyridine-6-carboxamide;Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]-
CBNumber:
CB88678799
Molecular Formula:
C25H32N6O3S
Molecular Weight:
496.62
MDL Number:
MFCD34475601
MOL File:
2597186-19-9.mol
Last updated:2024-07-02 08:55:39
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Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]- Properties

Density 1.41±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 93 mg/mL (187.26 mM);Ethanol: 5 mg/mL (10.07 mM)
pka 6.96±0.50(Predicted)
form Solid
color White to off-white
Water Solubility Water: Insoluble

Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]- Chemical Properties,Uses,Production

Biological Activity

SR-0813 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC50 values of 25 and 311 nM for ENL YEATS domain and AF9 YEATS domain, respectively.

References

[1] Garnar-Wortzel L, et al. ACS Cent Sci. 2021 May 26;7(5):815-830.

Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]- Suppliers

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Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
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Supplier Advantage
Nantong HI-FUTURE Biology Co., Ltd. 		58
Wuhan Han Sheng New Material Technology Co.，Ltd 		58
Nanjing Bicbiotechnology Co., Ltd 		58
ChemShuttle, Inc. 62
TaiChem Taizhou Limited 58
Shanghai Rechem science Co., Ltd. 58
DC Chemicals 58
SHANDONG OCTAGON CHEMICALS LIMITED 58
Chunchuang (Wuhan) Technology Co., Ltd 58
Nantong Hi-Future Biotechnology Co., Ltd 58
Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]- N-cyclobutyl-2-(3-((N-(2-(piperidin-1-yl)ethyl)sulfamoyl)amino)phenyl)imidazo[1,2-a]pyridine-6-carboxamide SR0813,SR 0813 2597186-19-9 APIs