Melitracen hydrochloride
- CAS No.
- 10563-70-9
- Chemical Name:
- Melitracen hydrochloride
- Synonyms
- Adaptol;Thymeol;U-24973A;Melixeran;Trausabun;Adaptol-d6;Thymeol-d6;Melixeran-d6;Trausabun-d6;Melitracene-d6
- CBNumber:
- CB8874744
- Molecular Formula:
- C21H26ClN
- Molecular Weight:
- 327.89084
- MDL Number:
- MFCD00242905
- MOL File:
- 10563-70-9.mol
- MSDS File:
- SDS
Melting point | 245-248°C |
---|---|
storage temp. | Sealed in dry,Room Temperature |
solubility | Soluble in DMSO |
form | Solid |
color | White to Off-White |
CAS DataBase Reference | 10563-70-9(CAS DataBase Reference) |
FDA UNII | J3448GKP5W |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Toxicity | LD50 i.v. in mice: 52 mg/kg (Petersen) |
Melitracen hydrochloride price More Price(29)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | M215500 | MelitracenHydrochloride | 10563-70-9 | 10mg | $155 | 2021-12-16 | Buy |
Usbiological | 015892 | Melitracen-d6 Hydrochloride | 10563-70-9 | 1mg | $446 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD71923 | Melitracen hydrochloride | 10563-70-9 | 5G | $450 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD71923 | Melitracen hydrochloride | 10563-70-9 | 2g | $250 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 18692 | MelitracenHCl | 10563-70-9 | 5mg | $950 | 2021-12-16 | Buy |
Melitracen hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Originator
Trausabun,Lusofarma,W. Germany,1965
Uses
Antidepressant
Definition
ChEBI: Melitracen hydrochloride is a member of anthracenes.
Manufacturing Process
24 g of 2-o-benzoylphenylpropanol-2 (MP 116°C) were dissolved in 250 ml of anhydrous ether and the resulting solution was added dropwise while stirring to a suspension of 0.22 mol of dimethylaminopropylmagnesium chloride in 100 ml of ether. The reaction mixture was refluxed for one hour on a steam bath, and water and dilute hydrochloric acid were added until the reaction was pH 4-5. The aqueous phase was separated and 60 ml of concentrated aqueous ammonia were added. The mixture was extracted with ether, and the ether phase was separated, dried and evaporated in a steam bath. The residue was dissolved in hot petroleum ether and the solution left standing to cool for some time, whereupon 4-dimethylamino-1-phenyl-1-[2-(2-hydroxy-2- propyl)phenyl]-butanol-1 crystallized out as white crystals which were sucked off. After drying they melted at 88°C to 90°C.
10 g of this compound were cautiously dissolved in 50 ml of concentrated
sulfuric acid under cooling and the mixture was kept at room temperature for
24 hours, whereupon the reaction mixture was poured into 200 g of finely
crushed ice, and concentrated aqueous ammonia was added to about pH 9,
whereupon the oil which separated out was extracted with ether. The ether
phase was separated, dried and the ether evaporated on a steam bath. The
residue was dissolved in 20 ml of acetone and the solution neutralized with a
solution of dry hydrogen chloride in ether. The white crystals of 9-γdimethylaminopropylidene-10,10-dimethyl-9,10-dihydroanthracene
hydrochloride which separated out was filtered off and dried. Yield 9 g. MP
245°C to 247°C.
Therapeutic Function
Antidepressant
Melitracen hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12832 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5857 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Shandong ruiyue Biological Technology Co.,Ltd. | 008615066100122(Lily wechat) | 513075341@qq.com | CHINA | 52 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
View Lastest Price from Melitracen hydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-27 | Melitracen hydrochloride
10563-70-9
|
US $0.00-0.00 / Kg/Bag | 100g | 99%min | 1000G | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-18 | Melitracen hydrochloride
10563-70-9
|
US $39.00-89.00 / mg | 99.82% | 10g | TargetMol Chemicals Inc. | |||
2024-10-25 | Melitracen hydrochloride
10563-70-9
|
US $0.00 / KG | 25KG | 0.99 | 50MT/month | Hebei Yanxi Chemical Co., Ltd. |
- Melitracen hydrochloride
10563-70-9
- US $0.00-0.00 / Kg/Bag
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- Melitracen hydrochloride
10563-70-9
- US $39.00-89.00 / mg
- 99.82%
- TargetMol Chemicals Inc.
- Melitracen hydrochloride
10563-70-9
- US $0.00 / KG
- 0.99
- Hebei Yanxi Chemical Co., Ltd.