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(R)-2-Phenylpyrrolidine

(R)-2-Phenylpyrrolidine Structure
(R)-2-Phenylpyrrolidine structure
CAS No.
56523-47-8
Chemical Name:
(R)-2-Phenylpyrrolidine
Synonyms
56523-47-8;(R)-2-Phenylpyrrolidine;(2R)-2-phenylpyrrolidine;Pyrrolidine, 2-phenyl-, (2R)-
CBNumber:
CB8875433
Molecular Formula:
C10H13N
Molecular Weight:
147.22
MDL Number:
MFCD06762513
MOL File:
56523-47-8.mol
Last updated:2023-09-27 17:58:14
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(R)-2-Phenylpyrrolidine Properties

Boiling point 120 °C(Press: 6 Torr)
Density 0.988±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 10.13±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(R)-2-Phenylpyrrolidine price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P998488 (R)-2-Phenylpyrrolidine 56523-47-8 100mg $265 2021-12-16 Buy
AK Scientific 9228AJ (R)-2-Phenylpyrrolidine 56523-47-8 250mg $278 2021-12-16 Buy
Activate Scientific AS43654 (R)-2-Phenylpyrrolidine 95% ee 56523-47-8 250mg $342 2021-12-16 Buy
Activate Scientific AS43654 (R)-2-Phenylpyrrolidine 95% ee 56523-47-8 100mg $171 2021-12-16 Buy
AK Scientific 9228AJ (R)-2-Phenylpyrrolidine 56523-47-8 1g $616 2021-12-16 Buy
Product number Packaging Price Buy
P998488 100mg $265 Buy
9228AJ 250mg $278 Buy
AS43654 250mg $342 Buy
AS43654 100mg $171 Buy
9228AJ 1g $616 Buy

(R)-2-Phenylpyrrolidine Chemical Properties,Uses,Production

Description

(R)-2-Phenylpyrrolidine is a boronic ester that can be administered orally. It has been shown to have nootropic and memory-enhancing activities in rats, but it does not have any known effects on kinase activities, amines, factor receptors, or synthetic activity.

Uses

(R)-2-Phenylpyrrolidine has also been shown to have prognostic value in cancer patients and can inhibit the growth of human cancer cells. This drug has been shown to bind to tropomyosin and growth factors with high affinity.

Definition

(R)-2-Phenylpyrrolidine is a novel class of selective pan-TRK inhibitors with efficacy in a KM12 rat tumor model. Since it was reported, this moiety has become a privileged TRK structure and was incorporated effectively in closely related scaffolds and on unrelated bicycle scaffolds. Its optimal shape complementarity to the TRK protein’s hydrophobic pocket available in the “DFG-in” conformation[1].

Origin

(R)-2-phenylpyrrolidine was first reported in 2008 by Ferrand S et al.

Properties and Applications

(R)-2-Phenylpyrrolidine is a yellow crystal,it is used as a pharmaceutical intermediate.

References

[1] Choi H, et al. (R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors. ACS Medicinal Chemistry Letters, 2015; 14: 562–567.

(R)-2-Phenylpyrrolidine synthesis

313352-62-4
56523-47-8
Synthesis of (R)-2-Phenylpyrrolidine from (5R)-5-phenyl-2-Pyrrolidinone

(R)-2-Phenylpyrrolidine Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-2-Phenylpyrrolidine Suppliers

Global( 86)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
Blocksynth Pharmaceutical Technology Co.,Ltd 		0086-19817745290; +8619817745290 bd@blocksynth.com China 5657 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Hangzhou Huarong Pharm Co., Ltd. 		571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3148 58
Golden Pharma Co., Limited 		+undefined18958062155 sales@zjgoldpharm.com China 5899 58
Tianjin Xinghan Biotechnology Co., Ltd 		+8618698089028 1725517238@qq.com China 2479 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658 sales1@artkmedchem.com China 39004 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
CONIER CHEM AND PHARMA LIMITED 		58
Career Henan Chemica Co 		58
Blocksynth Pharmaceutical Technology Co.,Ltd 		58
Hefei Hirisun Pharmatech Co., Ltd 		58
Hangzhou Huarong Pharm Co., Ltd. 		58
Golden Pharma Co., Limited 		58
Tianjin Xinghan Biotechnology Co., Ltd 		58
Aladdin Scientific 		58
Suzhou ARTK Medchem Co., Ltd. 		58

View Lastest Price from (R)-2-Phenylpyrrolidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-2-Phenylpyrrolidine pictures 2024-10-22 (R)-2-Phenylpyrrolidine
56523-47-8
 US $0.37 / KG 1KG 99% 10kg/100kg Career Henan Chemica Co

(R)-2-Phenylpyrrolidine Spectrum

(R)-2-Phenylpyrrolidine(56523-47-8)1HNMR

56523-47-8((R)-2-Phenylpyrrolidine)Related Search:

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(R)-2-(4-BROMOPHENYL)PYRROLIDINE (R)-2-(4-CHLOROPHENYL)PYRROLIDINE METHYL-2-PYRROLIDONE (R)-2-(4-Fluorophenyl)pyrrolidine 3-(4-Nitrophenyl)Pyrrolidine Hydrochloride
2-(4-Fluorophenyl)-pyrrolidine 3-(2-Methylphenyl)Pyrrolidine Hydrochloride 3-(4-(TRIFLUOROMETHYL)PHENYL)PYRROLIDINE HYDROCHLORIDE 2-(2-Fluorophenyl)pyrrolidine (3S,4R)-4-P-TOLYLPYRROLIDINE-3-CARBOXYLIC ACID
(3S,4R)-4-Phenylpyrrolidin-3-ol hydrochloride 3-(3-FLUOROPHENYL)PYRROLIDINE (2S,5R)-FMOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID

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(R)-2-Phenylpyrrolidine (2R)-2-phenylpyrrolidine 56523-47-8 Pyrrolidine, 2-phenyl-, (2R)- 56523-47-8 pharmaceutical intermediate Chiral heterocyclic compounds