hexafluronium bromide
- CAS No.
- 317-52-2
- Chemical Name:
- hexafluronium bromide
- Synonyms
- Milaxen;Mylaxen;Hexafluorenium;Esafluronio bromuro;HexafluoreniumBromide;hexafluronium bromide;Hexafluorenium dibromide
- CBNumber:
- CB8898197
- Molecular Formula:
- C36H42Br2N2
- Molecular Weight:
- 662.54008
- MDL Number:
- MFCD00867695
- MOL File:
- 317-52-2.mol
Melting point | 188-189° |
---|---|
Density | 1.1954 (rough estimate) |
refractive index | 1.6800 (estimate) |
FDA UNII | B64NJG83K2 |
hexafluronium bromide Chemical Properties,Uses,Production
Originator
Mylaxen,Mallinckrodt
Uses
Hexafluorenium Bromide is a cholinesterase inhibitor.
Uses
Relaxant (skeletal muscle); synergist (succinylcholine).
Manufacturing Process
2 Methods of producing of hexamethylene bis(2-fluorenyldimethylammonium)
dibromide:
1. To a solution of 13.2 g (0.054 mole) of 9-bromofluorene in 200 ml of
acetonitrile was added 3.1 g (0.018 mole) of 1,6-bis(dimethylamino)hexane.
Heat was evolved and solid began to precipitate immediately. After the initial
reaction had subsided the mixture was refluxed for 3.5 h on a steam bath.
The solid was collected and recrystallized three times from propanol to give
10.66 g (89% of the theoretical yield based on alkylenediamine) of
hexamethylene bis(9-fluorenyldimethylammonium) dibromide, as white
crystals melting at 188°-189°C.
2. A mixture of 4.18 g (0.02 mole) of 2-dimethylaminofluorene and 1.22 g
(0.005 mole) of 1,6-dibromohexane was heated at 115°C for 24 h, after
which time 10 ml of dry dioxane was added and the mixture refluxed for an
additional 37 h. The solid was filtered off washed with hot acetonitrile and
twice recrystallized from propanol to give 0.45 g of hexamethylene bis(2-
fluorenyldimethylammonium) dibromide, melting at 220°-222°C.
brand name
Mylaxen (Medpointe).
Therapeutic Function
Muscle relaxant
hexafluronium bromide Preparation Products And Raw materials
Raw materials
Preparation Products
hexafluronium bromide Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19885 | 58 |
Aikon International Limited | 025-66113011 18112977050 | cb6@aikonchem.com | China | 15494 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
Nanjing Bic Biotechnology Co., Ltd | 025-58906079 17352406906 | sales@bicbiotech.com | China | 7679 | 58 |
United States Biological | -- | sales@advtechind.com | United States | 6075 | 58 |
View Lastest Price from hexafluronium bromide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-28 | Hexafluronium Bromide
317-52-2
|
US $1980.00-2500.00 / mg | 10g | TargetMol Chemicals Inc. |
- Hexafluronium Bromide
317-52-2
- US $1980.00-2500.00 / mg
- TargetMol Chemicals Inc.