Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-

4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-

4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]- Structure
4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]- structure
CAS No.
1159408-64-6
Chemical Name:
4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-
Synonyms
G1-22;ZGN-002;Tri-GalNAc(OAc)3;6-[4-[N-[3-[3-[3-[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(Acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]-2-[[2-[N-[3-[5-[(5R,2R,3R;(2R,3R,4R,5R,6R)-3,4-bis(acetyloxy)-6-{4-[(3-{3-[2-amino-3-(2-{[3-(5-{[(2R,3R,4R,5R,6R)-4,5-bis(acetyloxy)-6-[(acetyloxy)methyl]-3-acetamidooxan-2-yl]oxy}pentanamido)propyl]carbamoyl}ethoxy)-2-[(2-{[3-(5-{[(2R,3R,4R,5R,6R)-4,5-bis(acetyloxy)-6-[(acetylox;4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl...;4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-;6-[4-[N-[3-[3-[3-[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(Acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]-2-[[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]methyl]-2-aminopropoxy]propanoylamino]propyl]carbamoyl]butoxy](3R;6-[4-[N-[3-[3-[3-[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(Acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]-2-[[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]methyl]-2-aminopropoxy]propanoylamino]propyl]carbamoyl]butoxy](3R,2R,4R,5R,6R)-5-(acetylamino)-4-acetyloxy-2-(acetyloxymethyl)-2H-3,4,5,6-tetrahydropyran-3-yl Acetat
CBNumber:
CB89017977
Molecular Formula:
C79H128N10O36
Molecular Weight:
1793.93
MDL Number:
MOL File:
1159408-64-6.mol
Last updated:2024-07-02 08:55:39
Request For Quotation

4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]- Properties

Boiling point 1585.5±65.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
pka 13.13±0.70(Predicted)
form Solid
color White to off-white

4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]- Chemical Properties,Uses,Production

Description

VPN08646 is a triantenerrary N-acetylgalactosamine (tri-GalNAc) with an amino group, which is useful precursor for synthesis of GalNAc-LYTAC that engage the asialoglycoprotein receptor for targeted protein degradation. VPN08646 was first reported in Nat Chem Biol. 2021 Sep;17(9):937-946 (compound ). This product has no formal name at the moment.

4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]- Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
Changsha Morning Shine Co., Ltd. 18975870350 13397510867 liyan@csmspharm.com China 263 58
Wuhu Huaren Science and Technology Co., Ltd. 0553-0553-5842013-801 18155347026 jinhuaren@huarensh.com China 744 58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd. 19981275275 sales@zsdbiopharm.com China 284 58
Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd. 13414494621 chenchao02lzu@126.com China 122 58
Wuhan Ruilida Biomedical Technology Co., Ltd. 18201884268 magean83@163.com China 1627 58
Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd 0371-037188900765 18037465274 3430974218@qq.com China 13793 58
Shanghai fuxiang biotechnology co., ltd 13611719524 2674347328@qq.com China 59 58
LinkChem Co.,Ltd. 21-21-20222982 13124863828 sales@linkchem.cn China 2958 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 18112977050 cb5@aikonchem.com China 10526 58
Shanghai Inchman Chemical Technology Co., LTD 18299177127 18299177127 info@richmanchem.com China 3000 58
Supplier Advantage
Changsha Morning Shine Co., Ltd. 58
Wuhu Huaren Science and Technology Co., Ltd. 58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd. 58
Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd. 58
Wuhan Ruilida Biomedical Technology Co., Ltd. 58
Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd 58
Shanghai fuxiang biotechnology co., ltd 58
LinkChem Co.,Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 58
Shanghai Inchman Chemical Technology Co., LTD 58
(2R,3R,4R,5R,6R)-3,4-bis(acetyloxy)-6-{4-[(3-{3-[2-amino-3-(2-{[3-(5-{[(2R,3R,4R,5R,6R)-4,5-bis(acetyloxy)-6-[(acetyloxy)methyl]-3-acetamidooxan-2-yl]oxy}pentanamido)propyl]carbamoyl}ethoxy)-2-[(2-{[3-(5-{[(2R,3R,4R,5R,6R)-4,5-bis(acetyloxy)-6-[(acetylox 4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]- Tri-GalNAc(OAc)3 4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl... 6-[4-[N-[3-[3-[3-[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(Acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]-2-[[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]methyl]-2-aminopropoxy]propanoylamino]propyl]carbamoyl]butoxy](3R,2R,4R,5R,6R)-5-(acetylamino)-4-acetyloxy-2-(acetyloxymethyl)-2H-3,4,5,6-tetrahydropyran-3-yl Acetat ZGN-002 6-[4-[N-[3-[3-[3-[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(Acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]-2-[[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]methyl]-2-aminopropoxy]propanoylamino]propyl]carbamoyl]butoxy](3R G1-22 6-[4-[N-[3-[3-[3-[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(Acetylamino)-4,5-diacetyloxy-6-(acetyloxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]pentanoylamino]propyl]carbamoyl]ethoxy]-2-[[2-[N-[3-[5-[(5R,2R,3R 1159408-64-6 C79H128N10O36 GalNAc