ChemicalBook >> CAS DataBase List >>Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]-
Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]-
![Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]- Structure](CAS/20210305/GIF/1965248-01-4.gif)
- CAS No.
- 1965248-01-4
- Chemical Name:
- Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]-
- Synonyms
- KDM2B-IN-2;KDM2B IN 2,KDM-2B-IN-2,KDM2BIN2;Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]-;1-Cyclobutyl-4-(1-((4-(thiophen-3-yl)phenyl)sulfonyl)-4,5-dihydro-1H-imidazol-2-yl)piperazine
- CBNumber:
- CB89834484
- Molecular Formula:
- C21H26N4O2S2
- Molecular Weight:
- 430.59
- MDL Number:
- MOL File:
- 1965248-01-4.mol
Last updated:2024-07-02 08:55:39
Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]- Properties
| Boiling point | 562.0±60.0 °C(Predicted) |
|---|---|
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 31.25 mg/mL (72.57 mM; ultrasonic and heat to 80°C) |
| form | Solid |
| pka | 7.89±0.70(Predicted) |
| color | White to light brown |
Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]- Chemical Properties,Uses,Production
Biological Activity
KDM2B-IN-2, a potent histone demethylase (kdm2b) inhibitor with an IC50 of 0.021 μM in a KDM2B TR-FRET assay. KDM2B-IN-2 can be used for hyperproliferative diseases research[1].
References
[1]. Brian K. Albrecht, et al. 4,5-dihydroimidazole derivatives and their use as histone demethylase (kdm2b) inhibitors. Patent WO2016112251A1.
Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]- Preparation Products And Raw materials
Raw materials
Preparation Products
Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]- Suppliers
Global( 6)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3732 | 55 |
| Bide Pharmatech Ltd. | 400-1647117 15221909166 | product02@bidepharm.com | China | 63720 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | 2853979810@qq.com | China | 10010 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9282 | 58 |
Piperazine, 1-cyclobutyl-4-[4,5-dihydro-1-[[4-(3-thienyl)phenyl]sulfonyl]-1H-imidazol-2-yl]-
KDM2B-IN-2
KDM2B IN 2,KDM-2B-IN-2,KDM2BIN2
1-Cyclobutyl-4-(1-((4-(thiophen-3-yl)phenyl)sulfonyl)-4,5-dihydro-1H-imidazol-2-yl)piperazine
1965248-01-4