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ChemicalBook >> CAS DataBase List >>1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl-

1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl-

1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl- Structure
1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl- structure
CAS No.
2579696-76-5
Chemical Name:
1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl-
Synonyms
COQ7-IN-2;1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl-
CBNumber:
CB89835188
Molecular Formula:
C15H13N3O
Molecular Weight:
251.28
MDL Number:
MOL File:
2579696-76-5.mol
Last updated:2024-11-19 23:02:33
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1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl- Properties

Boiling point 480.4±45.0 °C(Predicted)
Density 1.22±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 25 mg/mL (99.49 mM; Need ultrasonic)
pka 7.15±0.50(Predicted)
form Solid
color White to off-white

1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl- Chemical Properties,Uses,Production

Biological Activity

COQ7-IN-2 (compound 12) is an inhibitor of COQ7, witn IC50 values of 7.3 μM and 15.4 μM for DMQ10 and UQ10 accumulation, respectively[1]. COQ7-IN-2 (compound 12) has less growth inhibition against human normal culture cells[1].The substantial DMQ10 accumulation occurred in both PANC-1 cells (8.7% by COQ7-IN-2 (compound 12)) and PC3 cells (14.0% by COQ7-IN-2 (compound 12))[1].

References

[1]. Keiko Tsuganezawa, et al. Identification of small molecule inhibitors of human COQ7. Bioorg Med Chem. 2020 Jan 1;28(1):115182.

1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		support@targetmol.com United States 38632 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19705 58
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013 780229652@qq.com China 1163 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shaoguan Qicheng Biotechnology Co., Ltd 58

View Lastest Price from 1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
COQ7-IN-2 pictures 2024-11-19 COQ7-IN-2
2579696-76-5
 US $227.00-997.00 / mg 10g TargetMol Chemicals Inc.
  • COQ7-IN-2 pictures
  • COQ7-IN-2
    2579696-76-5
  • US $227.00-997.00 / mg
  • TargetMol Chemicals Inc.
1H-Pyrazol-5-ol, 1-(5-methyl-2-pyridinyl)-3-phenyl- COQ7-IN-2 2579696-76-5