7-Deaza-7-Propargylamino-3′-Azidomethyi-dGTP
- CAS No.
- 666847-81-0
- Chemical Name:
- 7-Deaza-7-Propargylamino-3′-Azidomethyi-dGTP
- Synonyms
- 7-Deaza-7-Propargylamino-3′-Azidomethyi-dGTP;7-Deaza-7-Propargylamino-3'-azidomethyl-dGTP;7-Deaza-7-Propargylamino-3'-azidomethyl-dGTP;7-Deaza-7-Propargylamino-3'-azidomethyl-2'-deoxyguanosine-5'-Triphosphate;3'-O-azidomethyl-7-deaza-7-[3-(2,2,2-trifluoroacetamido)-prop-1-ynyl]-2'-deoxyguanosine 5'-O-nucleoside triphosphate;4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-(3-amino-1-propyn-1-yl)-7-[3-O-(azidomethyl)-2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-erythro-pentofuranosyl]-3,7-dihydro-
- CBNumber:
- CB89855861
- Molecular Formula:
- C15H21N8O13P3
- Molecular Weight:
- 614.3
- MDL Number:
- MOL File:
- 666847-81-0.mol
7-Deaza-7-Propargylamino-3′-Azidomethyi-dGTP Chemical Properties,Uses,Production
Description
7-Deaza-7-Propargylamino-3′-Azidomethyl-dGTP is a key building block for preparing fluorescent conjugates that are used in the next generation sequencing (NGS). NGS uses a similar chain termination method to the earlier Sanger sequencing, but NGS is carried out by fluorescence-labeled nucleotide analogs acting as reversible terminators of the amplification reaction.
Uses
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS)[1].
References
[1] Peng Peng, et al. A novel target enrichment strategy in next-generation sequencing through 7-deaza-dGTP-resistant enzymatic digestion. BMC Res Notes. 2020 Sep 18;13(1):445. DOI:10.1186/s13104-020-05292-y
7-Deaza-7-Propargylamino-3′-Azidomethyi-dGTP Preparation Products And Raw materials
Raw materials
Preparation Products
7-Deaza-7-Propargylamino-3′-Azidomethyi-dGTP Suppliers
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