ANTI-LAG-3
- CAS No.
- Chemical Name:
- ANTI-LAG-3
- Synonyms
- ANTI-LAG-3;Anti-FDC protein;Anti-CD223 antigen;Anti-LAG3 antibody produced in rabbit;ANTI-LYMPHOCYTE ACTIVATION GENE-3 PROTEIN;Anti-Lymphocyte activation gene 3 protein precursor
- CBNumber:
- CB9104686
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03791833
- MOL File:
- Mol file
ANTI-LAG-3 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB1401228 | Anti-LAG3 antibody produced in rabbit purified immunoglobulin, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA013967 | Anti-LAG3 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA013967 | Anti-LAG3 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $282 | 2023-06-20 | Buy |
ANTI-LAG-3 Chemical Properties,Uses,Production
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
The protein lymphocyte-activation gene 3 encoded by the gene LAG-3 is expressed by various lymphoid cell types and plasmacytoid dendritic cells.
Biochem/physiol Actions
The gene LAG3 (lymphocyte-activation gene 3) encodes a member of the Ig superfamily. The encoded protein is a CD4-related molecule that interacts with and binds to MHC class II. It functions in the regulation of plasmacytoid dendritic cell homeostasis. It is expressed by activated natural CD4+CD25+ Tregs (regulatory T cells) and enhances the suppressor activity of CD4+ T cells towards effector T cells. It is involved in the regulation of Treg homeostasis and function, apart from mediating induced Treg development. This immune inhibitory molecule also functions in mitigating dendritic cell differentiation and function. It functions in synergy with programmed cell death 1 (PD-1) to facilitate tumoral immune escape.
ANTI-LAG-3 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-LAG-3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hao Zhun Biological Technology Co., Ltd. | -- | info@zzsrm.com | CHINA | 6846 | 58 |
| Beijing Bai Ao Si Biotechnology Co., Ltd. | -- | yangmei@bioneeds.net | CHINA | 6999 | 58 |
| Shanghai Hao Biological Technology Co., Ltd. | -- | shxiyuanbio@163.com | CHINA | 6921 | 58 |
| Beijing Taize Ruida Technology Co., Ltd. | -- | taizeorder@163.com | CHINA | 6536 | 58 |
| Beijing Fubo Biotechnology Co., Ltd. | -- | info@f-biology.com | CHINA | 6039 | 58 |
| Beijing Qiangxin Borui Biotechnology Co., Ltd. | -- | moumou@xxx.com | CHINA | 2992 | 58 |
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| Vision BioSystems | -- | sales.usa@vision-bio.com | United States | 542 | 74 |