Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride

(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride

(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride Structure
(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride structure
CAS No.
130209-90-4
Chemical Name:
(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride
Synonyms
(+/-)-Clopidogrelhydrochloride;(+/-)-Clopidogrel hydrochloride DISCONTINUED;(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetateHCl;Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate hydrochloride;METHYL 2-(2-CHLOROPHENYL)-2-(4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDIN-5-YL)ACETATE HYDROCHLORIDE;(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride
CBNumber:
CB91074784
Molecular Formula:
C16H17Cl2NO2S
Molecular Weight:
358.28
MDL Number:
MOL File:
130209-90-4.mol
Last updated:2023-06-30 15:45:59
Request For Quotation

(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride Properties

storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.33 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid

(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13657 (±)-Clopidogrel (hydrochloride) 130209-90-4 10mg $138 2024-03-01 Buy
Cayman Chemical 13657 (±)-Clopidogrel (hydrochloride) 130209-90-4 50mg $606 2024-03-01 Buy
Tocris 2490 (+/-)-Clopidogrelhydrochloride ≥99%(HPLC) 130209-90-4 50 $724 2021-12-16 Buy
AK Scientific 2760DA (+/-)-Clopidogrelhydrochloride 130209-90-4 50mg $775 2021-12-16 Buy
AK Scientific 2760DA (+/-)-Clopidogrelhydrochloride 130209-90-4 10mg $251 2021-12-16 Buy
Product number Packaging Price Buy
13657 10mg $138 Buy
13657 50mg $606 Buy
2490 50 $724 Buy
2760DA 50mg $775 Buy
2760DA 10mg $251 Buy

(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride Chemical Properties,Uses,Production

Description

Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM).1,2 Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite via CYP2C19 in the liver enables its anti-aggregating activity.3 Marketed under the name Plavix?, clopidogrel in combination with aspirin has been shown to be beneficial in the prevention of vascular ischemic events for patients without deficiencies in CYP2C19-related metabolism.4

storage

+4°C (desiccate)

References

1. Savi, P., Labouret, C., Delesque, N., et al. P2Y12, a new platelet ADP receptor, target of clopidogrel Biochem. Bioph. Res. Commun. 283(2),379-383(2001).
2. von Kügelgen, I. Pharmacological profiles of cloned mammalian P2Y-receptor subtypes Pharmacol. Ther. 110(3),415-432(2006).
3. Quinn, M.J., and Fitzgerald, D.J. Ticlopidine and clopidogrel Circulation 100(15),1667-1672(1999).
4. Angiolillo, D.J., Fernandez-Ortiz, A., Bernardo, E., et al. Variability in individual responsiveness to clopidogrel: Clinical implications, management, and future perspectives J. Am. Coll. Cardiol. 49(14),1505-1516(2007).

(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

(R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30253 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 3058 58
Wuhan Yuxiang Medical Technology Co., Ltd. 13971275651 sales@whyxpharma.com China 4352 58
Supplier Advantage
Career Henan Chemica Co 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
Guangzhou Isun Pharmaceutical Co., Ltd 55
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
Nantong Hi-Future Biotechnology Co., Ltd 58
Wuhan Yuxiang Medical Technology Co., Ltd. 58
METHYL 2-(2-CHLOROPHENYL)-2-(4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDIN-5-YL)ACETATE HYDROCHLORIDE (R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetateHCl (R,S)-Methyl-2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothino[3.2-c]pyridin-5-yl)acetatehydrochloride (+/-)-Clopidogrelhydrochloride (+/-)-Clopidogrel hydrochloride DISCONTINUED Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate hydrochloride 130209-90-4