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ChemicalBook >> CAS DataBase List >>1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)-

1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)-

1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- Structure
1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- structure
CAS No.
2477650-96-5
Chemical Name:
1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)-
Synonyms
USP8-IN-1;1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)-
CBNumber:
CB911108589
Molecular Formula:
C18H21N5O3S
Molecular Weight:
387.46
MDL Number:
MOL File:
2477650-96-5.mol
Last updated:2024-07-02 08:55:39
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1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- Properties

Boiling point 603.0±65.0 °C(Predicted)
Density 1.397±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 125 mg/mL (322.61 mM; Need ultrasonic)
form Solid
pka 12.72±0.20(Predicted)
color Light yellow to green yellow

1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- Chemical Properties,Uses,Production

Biological Activity

USP8-IN-1 is a USP8 inhibitor with an IC50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI50 of 82.04 μM (CN111138358A; U10)[1].

References

[1]. Zhiyu Li, et al. USP8 inhibitor and preparation method and application thereof. CN111138358A.

1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32760 60
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 23963 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5587 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29978 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5012 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9274 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 58
Nanjing Tengyi Biotechnology Co., Ltd 58
https://hanhongsci.com/ 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
RD International Technology Co., Limited 58

1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- Spectrum

1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)-(2477650-96-5)1HNMR
1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- USP8-IN-1 2477650-96-5