ChemicalBook >> CAS DataBase List >>Geclosporin

Geclosporin

CAS No.
74436-00-3
Chemical Name:
Geclosporin
Synonyms
CS-2592;Geclosporin;cyclosporin G;Cyclosporine G;Cyclosporin G (9CI);Cyclosporin Impurity G;Cyclosporine Impurity G;Cyclosporine Impurity 7;Ring spore fungus element;Cyclosporin A, 7-L-norvaline-
CBNumber:
CB91117216
Molecular Formula:
C63H113N11O12
Molecular Weight:
1216.64
MDL Number:
MFCD00867600
MOL File:
74436-00-3.mol
Last updated:2023-04-23 13:52:06

Geclosporin Properties

Melting point 196-197°
alpha D20 -245° (c = 1.0 in chloroform); D20 -191° (c = 1.04 in methanol)
Boiling point 1297.8±65.0 °C(Predicted)
Density 1.013±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 13.32±0.70(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic
InChIKey ZMKGDQSIRSGUDJ-LIAWPGETNA-N
EWG's Food Scores 1
FDA UNII UA3JNW70T9

Geclosporin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C990143 CyclosporinG 74436-00-3 5mg $570 2021-12-16 Buy
American Custom Chemicals Corporation API0011154 CYCLOSPORIN G 95.00% 74436-00-3 5MG $501.6 2021-12-16 Buy
Product number Packaging Price Buy
C990143 5mg $570 Buy
API0011154 5MG $501.6 Buy

Geclosporin Chemical Properties,Uses,Production

Uses

Cylclosporin G is a derivative of Cyclosporin A (C989900), an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Uses

Cylclosporin G is a derivative of Cyclosporin A, an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Geclosporin Preparation Products And Raw materials

Raw materials

Preparation Products

Geclosporin Suppliers

Global( 61)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Excellent Biomedical Technology Co.,Ltd.
+86-0755-26050679 +86-15915472436 sale@ex-biotech.cn China 1031 58
Hangzhou FandaChem Co.,Ltd.
+8615858145714 FandaChem@Gmail.com China 9210 55
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Shenzhen Excellent Biotech Co., Ltd.
13480692018 ramyan@ex-biotech.com CHINA 954 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
LUYUNJIA CHEMISTRY XIAMEN LIMITED
+86-592-5360779 +86-13055435203 China 5988 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58
Geclosporin (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Nva-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) Cyclo(((2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl)-L-norvalyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl) Cyclosporin A, 7-L-norvaline- cyclosporin G Cyclosporine Impurity G Cyclosporin Impurity G CS-2592 Cyclosporine G/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-norvalyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] Cyclosporine G Ring spore fungus element Cyclosporin Impurity 7(Cyclosporin G) (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone Cyclosporine Impurity 7 Cyclosporin G (9CI) (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone 74436-00-3 C63H113N11O12