ChemicalBook >> CAS DataBase List >>8,10,12,14,19-Docosapentaenoic acid, 7,16,17-trihydroxy-, (7S,8E,10Z,12E,14E,16R,17S,19Z)-
8,10,12,14,19-Docosapentaenoic acid, 7,16,17-trihydroxy-, (7S,8E,10Z,12E,14E,16R,17S,19Z)-
- CAS No.
- 2093111-29-4
- Chemical Name:
- 8,10,12,14,19-Docosapentaenoic acid, 7,16,17-trihydroxy-, (7S,8E,10Z,12E,14E,16R,17S,19Z)-
- Synonyms
- Resolvin D2 n-3 DPA;8,10,12,14,19-Docosapentaenoic acid, 7,16,17-trihydroxy-, (7S,8E,10Z,12E,14E,16R,17S,19Z)-
- CBNumber:
- CB911188927
- Molecular Formula:
- C22H34O5
- Molecular Weight:
- 378.5
- MDL Number:
- MOL File:
- 2093111-29-4.mol
Last updated:2023-06-08 09:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
8,10,12,14,19-Docosapentaenoic acid, 7,16,17-trihydroxy-, (7S,8E,10Z,12E,14E,16R,17S,19Z)- Chemical Properties,Uses,Production
Biological Activity
Resolvin D2 n-3 DPA (RvD2 n-3 DPA) is a specialized pro-resolving mediator (SPM).1 It is formed from docosapentaenoic acid , an intermediate in the conversion of eicosapentaenoic acid to docosahexaenoic acid , in human leukocytes. RvD2 n-3 DPA (1 nM) reduces TNF-α-induced chemotaxis and adhesion of isolated human neutrophils. In vivo, RvD2 n-3 DPA (100 ng/animal; i.v.) reduces peritoneal neutrophil infiltration and exudate levels of IL-6 and chemokine (C-C motif) ligand 2 (CCL2) in a mouse model of zymosan-induced inflammation.
References
1.Dalli, J., Colas, R.A., and Serhan, C.N.Novel n-3 immunoresolvents: Structures and actionsSci. Rep.31940(2013)
8,10,12,14,19-Docosapentaenoic acid, 7,16,17-trihydroxy-, (7S,8E,10Z,12E,14E,16R,17S,19Z)- Preparation Products And Raw materials
Raw materials
Preparation Products
8,10,12,14,19-Docosapentaenoic acid, 7,16,17-trihydroxy-, (7S,8E,10Z,12E,14E,16R,17S,19Z)- Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11975 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19696 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
8,10,12,14,19-Docosapentaenoic acid, 7,16,17-trihydroxy-, (7S,8E,10Z,12E,14E,16R,17S,19Z)-
Resolvin D2 n-3 DPA
2093111-29-4