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Trichostatin C

CAS No.
68676-88-0
Chemical Name:
Trichostatin C
Synonyms
145-A;7-[4-(Dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-2,4-heptadienamide;2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-, (2E,4E,6R)-;7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide;(2E,4E)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide;(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide
CBNumber:
CB91120816
Molecular Formula:
C23H32N2O8
Molecular Weight:
464.51
MDL Number:
MFCD08061903
MOL File:
68676-88-0.mol
Last updated:2023-05-21 10:59:17

Trichostatin C Properties

Melting point 171-173°
alpha D24 +50.5 ±0.9° (c = 0.987 in methanol)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
pka 12.85±0.70(Predicted)
form White to off-white powder.
FDA UNII 8K9Y0C8YN4

Trichostatin C price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20220 Trichostatin C ≥95% 68676-88-0 500μg $290 2024-03-01 Buy
Cayman Chemical 20220 Trichostatin C ≥95% 68676-88-0 2.5mg $1159 2024-03-01 Buy
TRC T774713 TrichostatinC 68676-88-0 1000μg $475 2021-12-16 Buy
American Custom Chemicals Corporation API0017165 TRICHOSTATIN C 95.00% 68676-88-0 0.5MG $549 2021-12-16 Buy
Product number Packaging Price Buy
20220 500μg $290 Buy
20220 2.5mg $1159 Buy
T774713 1000μg $475 Buy
API0017165 0.5MG $549 Buy

Trichostatin C Chemical Properties,Uses,Production

Uses

Trichostatin C is an inducer of erythroid differentiation and histone H4 acetylation level.

Uses

Trichostatin C is the first example of a glucopyranosyl hydroxamate from nature. The conjugation may act to protect the less stable N-OH group of Trichostatin A. Trichostatin C displays antifungal, antiprotozoan and antitumour activity, albeit less potent than trichostatin A

Definition

ChEBI: Trichostatin C is a trichostatin and an O-amino sugar. It is functionally related to a trichostatin A.

Trichostatin C Preparation Products And Raw materials

Raw materials

Preparation Products

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7-[4-(Dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-2,4-heptadienamide 145-A 7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide (2E,4E)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide 2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-, (2E,4E,6R)- 68676-88-0 C23H32N2O8