HOMATROPINE METHYL BROMIDE
- CAS No.
- 80-49-9
- Chemical Name:
- HOMATROPINE METHYL BROMIDE
- Synonyms
- D02070;ESOPIN;sethyl;Equipin;homapin;mesopin;HOMOLONE;novatrin;sed-tems;endo-mid
- CBNumber:
- CB9114740
- Molecular Formula:
- C17H24BrNO3
- Molecular Weight:
- 370.28
- MDL Number:
- MFCD00050292
- MOL File:
- 80-49-9.mol
- MSDS File:
- SDS
| Melting point | 192°C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | Freely soluble in water, soluble in ethanol 96 per cent |
| form | Solid |
| color | White to Off-White |
| Merck | 14,4730 |
| CAS DataBase Reference | 80-49-9(CAS DataBase Reference) |
| FDA 21 CFR | 310.545 |
| FDA UNII | 68JRS2HC1C |
| ATC code | A03BB06 |
| EPA Substance Registry System | Homatropine methylbromide (80-49-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 22-26-36 | |||||||||
| RIDADR | 1544 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MS9000000 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29399990 | |||||||||
| Toxicity | LD50 in mice (mg/kg): 1400 orally, 60 i.p. (Cahen, Tvede) | |||||||||
| NFPA 704 |
|
HOMATROPINE METHYL BROMIDE price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3183 | Homatropine Methylbromide pharmaceutical secondary standard, certified reference material | 80-49-9 | 500MG | $200 | 2024-03-01 | Buy |
| Sigma-Aldrich | H0830000 | Homatropine methylbromide European Pharmacopoeia (EP) Reference Standard | 80-49-9 | h0830000 | $223 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1311000 | Homatropine methylbromide | 80-49-9 | 250mg | $394 | 2024-03-01 | Buy |
| TCI Chemical | H0448 | Homatropine Methyl Bromide | 80-49-9 | 5g | $41 | 2024-03-01 | Buy |
| TCI Chemical | H0448 | Homatropine Methyl Bromide | 80-49-9 | 25g | $124 | 2024-03-01 | Buy |
HOMATROPINE METHYL BROMIDE Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder or colourless crystals
Uses
Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.
Uses
anticholinergic (opthalmic)
brand name
Equipin (Mission); Homapin (Mission).
General Description
Homatropinemethylbromide, 3 -hydroxy-8-methyl-1 H,5 H-tropaniumbromide mandelate (Novatropine, Mesopin), occurs as a bitter,white, odorless powder and is affected by light. The compoundis readily soluble in water and alcohol but insoluble inether. The pH of a 1% solution is 5.9 and that of a 10% solutionis 4.5. Although a solution of the compound yields a precipitatewith alkaloidal reagents, such as mercuric potassiumiodide test solution, addition of alkali hydroxides or carbonatesdoes not cause the precipitate that occurs with nonquaternarynitrogen salts (e.g., atropine, homatropine).
Clinical Use
Homatropine methylbromide is transported poorly acrossthe blood-brain barrier because of its quaternary ammoniumgroup and, therefore, has far fewer stimulant properties thanatropine. It does have all the characteristic peripheralparasympathetic depressant properties of atropine and isused to reduce oversecretion and to relieve GI spasms.
HOMATROPINE METHYL BROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18779 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from HOMATROPINE METHYL BROMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | Homatropine Methyl Bromide
80-49-9
|
US $0.00 / KG | 1KG | 98.0% | 500kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-19 | Homatropine Methylbromide
80-49-9
|
US $36.00-59.00 / mg | 100% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | Homatropine Methylbromide
80-49-9
|
US $36.00-59.00 / mg | 100% | 10g | TargetMol Chemicals Inc. |
-
- Homatropine Methyl Bromide
80-49-9
- US $0.00 / KG
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Homatropine Methylbromide
80-49-9
- US $36.00-59.00 / mg
- 100%
- TargetMol Chemicals Inc.
-
- Homatropine Methylbromide
80-49-9
- US $36.00-59.00 / mg
- 100%
- TargetMol Chemicals Inc.