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ChemicalBook >> CAS DataBase List >>1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester

1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester

1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester Structure
1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester structure
CAS No.
723304-76-5
Chemical Name:
1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester
Synonyms
CCR8 antagonist 1;1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester
CBNumber:
CB911574573
Molecular Formula:
C26H29N3O5S
Molecular Weight:
495.59
MDL Number:
MOL File:
723304-76-5.mol
Last updated:2024-07-02 08:55:39
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1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester Properties

Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 25 mg/mL (50.44 mM; Need ultrasonic)
form Solid
pka 11.41±0.20(Predicted)
color White to off-white

1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester Chemical Properties,Uses,Production

Biological Activity

CCR8 antagonist 1 (compound 15) is a potente human CCR8 antagonist with a Ki of 1.6 nM[1].

References

[1]. Jenkins TJ, et al. Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. J Med Chem. 2007;50(3):566-584.

1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester Suppliers

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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32760 60
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9882 58
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Absin Bioscience Inc. 021-38015121 15000105423 chenjw@absin.cn China 24734 58
InvivoChem 13549236410 sales@invivochem.cn China 6749 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5593 58
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Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Aladdin Scientific 		58
Shanghai Chaolan Chemical Technology Center 58
Shanghai Yu Ben Biotechnology Co., Ltd. 58
Absin Bioscience Inc. 58
InvivoChem 58
TargetMol Chemicals Inc. 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester CCR8 antagonist 1 723304-76-5