Teicoplanin A2-5
- CAS No.
- 91032-38-1
- Chemical Name:
- Teicoplanin A2-5
- Synonyms
- teicoplanin A2-5;Teichomycin A2-5;Teicoplanin A2-5 DISCONTINUED. Please see T015500;34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-ristomycinAaglycone;Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-;Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(9-methyl-1-oxodecyl)amino-.beta.-D-glucopyranosyl-42-O-.alpha.-D-mannopyranosyl-
- CBNumber:
- CB91215185
- Molecular Formula:
- C89H99Cl2N9O33
- Molecular Weight:
- 1893.68
- MDL Number:
- MFCD01750327
- MOL File:
- 91032-38-1.mol
- MSDS File:
- SDS
Density | 1.67±0.1 g/cm3(Predicted) |
---|---|
storage temp. | Store at -20°C |
solubility | Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide |
form | lyophilisate |
pka | 2.88±0.40(Predicted) |
FDA UNII | 55234TX04D |
Teicoplanin A2-5 price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 20192 | Teicoplanin A2-5 ≥98% | 91032-38-1 | 1mg | $242 | 2024-03-01 | Buy |
Cayman Chemical | 20192 | Teicoplanin A2-5 ≥98% | 91032-38-1 | 5mg | $965 | 2024-03-01 | Buy |
ApexBio Technology | C4938 | TeicoplaninA2-5 | 91032-38-1 | 5mg | $1104 | 2021-12-16 | Buy |
AK Scientific | 6172CX | TeicoplaninA2-5 | 91032-38-1 | 5mg | $1174 | 2021-12-16 | Buy |
ApexBio Technology | C4938 | TeicoplaninA2-5 | 91032-38-1 | 1mg | $276 | 2021-12-16 | Buy |
Teicoplanin A2-5 Chemical Properties,Uses,Production
Uses
Teicoplanin A2-5 is an antibiotic against Gram positive bacteria.
Uses
Teicoplanin A2-5 is the most non-polar analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis.
Definition
ChEBI: A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group.
Biological Activity
teicoplanin a2-5, derived from actinoplanes teichomyceticus, is a glycopeptide antibiotic which produces a broad spectrum of antibiotic activity against gram-positive bacteria.teicoplanin a2-5 is the most non-polar metabolite in the family of teicoplanins. teicoplanin, previously referred to in the literature as teichomycin, is a mixture of five closely related components of similar polarity, designated t-a2-1, 2, 3, 4 and 5 and of one more polar component, designated t-a3. additionally, as a glycopeptide antibiotic belonging to the same family as vancomycin, teicoplanin blocks cell wall synthesis in bacillus subtilis, which is accompanied by an intracellular accumulation of udp-n-acetylmuramyl-pentapetide [1]. due to the greater antibacterial activity of teicoplanin than other agents, it has been thoroughly studied as a β-1actamase-resistant agent for the treatment of human infections caused by streptococci and staphylococci, including enterococci [2].
References
[1]. somma, s., gastaldo, l., & corti, a. teicoplanin, a new antibiotic from actinoplanes teichomyceticus nov. sp. antimicrobial agents and chemotherapy. 1984; 26(6): 917-923.
[2]. traina, g., & bonati, m. pharmacokinetics of teicoplanin in man after intravenous administration. journal of pharmacokinetics and biopharmaceutics. 1984;12(2): 119-128.
Teicoplanin A2-5 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18021 | 56 |
BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56077 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8864 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |