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Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-

Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- structure

CAS No.: 2309931-09-5

Chemical Name:: Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-

Synonyms: (R)-N-((1-((4-chlorophenyl)amino)-1-oxopropan-2-yl)oxy)-3,5-bis(trifluoromethyl)benzamide;Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-

CBNumber:: CB912280516

Molecular Formula:: C18H13ClF6N2O3

Molecular Weight:: 454.75

MDL Number:

MOL File:: 2309931-09-5.mol

Last updated:2023-07-12 16:34:29

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Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- Properties

Density	1.469±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml; Ethanol: 0.25 mg/ml
form	A crystalline solid
pka	12.58±0.70(Predicted)

Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	20106	(R)-CCG-1423 ≥98%	2309931-09-5	100 μg	$29	2024-03-01	Buy
Cayman Chemical	20106	(R)-CCG-1423 ≥98%	2309931-09-5	500 μg	$107	2024-03-01	Buy
Cayman Chemical	20106	(R)-CCG-1423 ≥98%	2309931-09-5	1 mg	$169	2024-03-01	Buy

Product number	Packaging	Price	Buy
20106	100 μg	$29	Buy
20106	500 μg	$107	Buy
20106	1 mg	$169	Buy

Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- Chemical Properties,Uses,Production

Description

(R)-CCG-1423 is a stereoisomer of CCG-1423 , a Rho inhibitor that blocks signaling through myocardin-related transcription factor A (MRTF-A) and serum response factor (SRF).^1,2 The R-isomer of CCG-1423 inhibits MRTF-A-dependent cellular events, including SRF-mediated gene expression and cell migration, less potently than the S-isomer.²

References

1. Evelyn, C.R., Wade, S.M., Wang, Q., et al. CCG-1423: A small-molecule inhibitor of RhoA transcriptional signaling Mol. Cancer Ther. 6(8),2249-2260(2007).
2. Watanabe, B., Minami, S., Ishida, H., et al. Stereospecific inhibitory effects of CCG-1423 on the cellular events mediated by myocardin-related transcription factor A PLoS One 10(8),(2015).

Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58

Supplier	Advantage
Shanghai Yifei Biotechnology Co. , Ltd.	58

Benzamide, N-[(1R)-2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- (R)-N-((1-((4-chlorophenyl)amino)-1-oxopropan-2-yl)oxy)-3,5-bis(trifluoromethyl)benzamide 2309931-09-5