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N,N'-Dimethylarginine

CAS No.
30344-00-4
Chemical Name:
N,N'-Dimethylarginine
Synonyms
SDMA-d6;SDMA, 10 mM in DMSO;N,N'-Dimethylarginine;H-Arg(Me, Me)-OH (sym);NG'-Dimethyl-L-arginine;Symmetric dimethylarginine;Nω,N'ω-dimethyl-L-arginine;NG,NG’-Dimethy-L-arginine-d6;L-Arg(Me, Me)-OH (syMMetrical);L-Arg(Me, Me)-OH (asyMMetrical)
CBNumber:
CB91236269
Molecular Formula:
C8H18N4O2
Molecular Weight:
202.25
MDL Number:
MFCD14705169
MOL File:
30344-00-4.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24

N,N'-Dimethylarginine Properties

Boiling point 353.5±52.0 °C(Predicted)
Density 1.22±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO : 50 mg/mL (247.22 mM; ultrasonic and adjust pH to 3 with 1M HCl)
pka 2.48±0.24(Predicted)
form Orange powder.
color White to off-white
Stability Very Hygroscopic
FDA UNII 49787G1ULV

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

N,N'-Dimethylarginine price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-6304 SDMA >98.0% 30344-00-4 100mg $103 2021-12-16 Buy
ChemScene CS-6304 SDMA >98.0% 30344-00-4 250mg $238 2021-12-16 Buy
ChemScene CS-6304 SDMA >98.0% 30344-00-4 1g $569 2021-12-16 Buy
AccelPharmtech OK1189 (2S)-2-aMino-5-[(N,N'-diMethylcarbaMiMidoyl)aMino]pentanoicacid 95.00% 30344-00-4 1G $570 2021-12-16 Buy
Chemenu CM322568 (S)-2-Amino-5-((bis(methylamino)methylene)amino)pentanoicacid 95% 30344-00-4 1g $645 2021-12-16 Buy
Product number Packaging Price Buy
CS-6304 100mg $103 Buy
CS-6304 250mg $238 Buy
CS-6304 1g $569 Buy
OK1189 1G $570 Buy
CM322568 1g $645 Buy

N,N'-Dimethylarginine Chemical Properties,Uses,Production

Chemical Properties

Beige to Pale Yellow Solid

Uses

N,N'-Dimethylarginine is an arginine derivative; used in chronic kidney diseases. A potential endogenous nitric oxide inhibitor in dialysis.

Definition

ChEBI: A L-arginine derivative having two methyl groups at the Nomega- and N'omega-positions

in vivo

SDMA is highly stable in serum and plasma, and the assay demonstrates excellent analytical performance. In unaffected dogs, SDMA remains unchanged whereas in affected dogs, SDMA increases during disease progression, correlating strongly with an increase in sCr and decrease in GFR[3].
Chronic SDMA infusion leads to a significant increase of SDMA levels in mice, but the GFR did not change at 4 weeks. No histological changes are observed, particularly no effect on fibrosis or endothelias nitric oxide synthase expression. There is neither an effect of SDMA on systolic blood pressure nor on ejection fraction[4].

IC 50

Human Endogenous Metabolite

N,N'-Dimethylarginine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 78)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29808 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32251 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 7859 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38653 58

View Lastest Price from N,N'-Dimethylarginine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N'-Dimethylarginine pictures 2025-04-17 N,N'-Dimethylarginine
30344-00-4
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
SDMA pictures 2024-11-19 SDMA
30344-00-4
US $34.00-101.00 / mg ≥98% 10g TargetMol Chemicals Inc.
N,N'-Dimethylarginine pictures 2020-01-09 N,N'-Dimethylarginine
30344-00-4
US $2.00 / KG 1g 98%min ask Career Henan Chemical Co
  • SDMA pictures
  • SDMA
    30344-00-4
  • US $34.00-101.00 / mg
  • ≥98%
  • TargetMol Chemicals Inc.
(2S)-2-amino-5-[(N,N'-dimethylcarbamimidoyl)amino]pentanoic acid L-Arg(Me, Me)-OH (syMMetrical) L-Arg(Me, Me)-OH (asyMMetrical) Symmetric dimethylarginine N5-[(Dimethylamino)iminomethyl]-L-ornithine-d6 N5-[Bis(methylamino)methylene]-L-ornithine-d6 NG,NG’-Dimethy-L-arginine-d6 SDMA-d6 (S)-2-Amino-5-((bis(methylamino)methylene)amino)pentanoic acid NG,NG'-Dimethy-L-arginine Solution, 100ppm NG'-Dimethyl-L-arginine Nω,N'ω-dimethyl-L-arginine L-Arg(Me,Me)-OH(symmetrical), >97% L-Ornithine,N5-[(methylamino)(methylimino)methyl]- N,N'-Dimethylarginine USP/EP/BP H-Arg(Me, Me)-OH (sym) inhibit,Inhibitor,Endogenous Metabolite,SDMA (2S)-2-amino-5-[(N,N-dimethylcarbamimidoyl)amino]pentanoic Symmetric dimethylarginine(SDMA) SDMA, 10 mM in DMSO N,N'-Dimethylarginine 30344-00-4 30135-93-6 C8H12D6N4O2 Isotope Labelled Compounds Amino Acids & Derivatives Intermediates & Fine Chemicals Isotope Labeled Compounds Pharmaceuticals