N,N'-Dimethylarginine
- CAS No.
- 30344-00-4
- Chemical Name:
- N,N'-Dimethylarginine
- Synonyms
- SDMA-d6;SDMA, 10 mM in DMSO;N,N'-Dimethylarginine;H-Arg(Me, Me)-OH (sym);NG'-Dimethyl-L-arginine;Symmetric dimethylarginine;Nω,N'ω-dimethyl-L-arginine;NG,NG’-Dimethy-L-arginine-d6;L-Arg(Me, Me)-OH (syMMetrical);L-Arg(Me, Me)-OH (asyMMetrical)
- CBNumber:
- CB91236269
- Molecular Formula:
- C8H18N4O2
- Molecular Weight:
- 202.25
- MDL Number:
- MFCD14705169
- MOL File:
- 30344-00-4.mol
- MSDS File:
- SDS
Boiling point | 353.5±52.0 °C(Predicted) |
---|---|
Density | 1.22±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO : 50 mg/mL (247.22 mM; ultrasonic and adjust pH to 3 with 1M HCl) |
pka | 2.48±0.24(Predicted) |
form | Orange powder. |
color | White to off-white |
Stability | Very Hygroscopic |
FDA UNII | 49787G1ULV |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
N,N'-Dimethylarginine price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-6304 | SDMA >98.0% | 30344-00-4 | 100mg | $103 | 2021-12-16 | Buy |
ChemScene | CS-6304 | SDMA >98.0% | 30344-00-4 | 250mg | $238 | 2021-12-16 | Buy |
ChemScene | CS-6304 | SDMA >98.0% | 30344-00-4 | 1g | $569 | 2021-12-16 | Buy |
AccelPharmtech | OK1189 | (2S)-2-aMino-5-[(N,N'-diMethylcarbaMiMidoyl)aMino]pentanoicacid 95.00% | 30344-00-4 | 1G | $570 | 2021-12-16 | Buy |
Chemenu | CM322568 | (S)-2-Amino-5-((bis(methylamino)methylene)amino)pentanoicacid 95% | 30344-00-4 | 1g | $645 | 2021-12-16 | Buy |
N,N'-Dimethylarginine Chemical Properties,Uses,Production
Chemical Properties
Beige to Pale Yellow Solid
Uses
N,N'-Dimethylarginine is an arginine derivative; used in chronic kidney diseases. A potential endogenous nitric oxide inhibitor in dialysis.
Definition
ChEBI: A L-arginine derivative having two methyl groups at the Nomega- and N'omega-positions
in vivo
SDMA is highly stable in serum and plasma, and the assay demonstrates excellent analytical performance. In unaffected dogs, SDMA remains unchanged whereas in affected dogs, SDMA increases during disease progression, correlating strongly with an increase in sCr and decrease in GFR[3].
Chronic SDMA infusion leads to a significant increase of SDMA levels in mice, but the GFR did not change at 4 weeks. No histological changes are observed, particularly no effect on fibrosis or endothelias nitric oxide synthase expression. There is neither an effect of SDMA on systolic blood pressure nor on ejection fraction[4].
IC 50
Human Endogenous Metabolite
N,N'-Dimethylarginine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32251 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7859 | 58 |
Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38653 | 58 |
View Lastest Price from N,N'-Dimethylarginine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-04-17 | N,N'-Dimethylarginine
30344-00-4
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
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2024-11-19 | SDMA
30344-00-4
|
US $34.00-101.00 / mg | ≥98% | 10g | TargetMol Chemicals Inc. | ||
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2020-01-09 | N,N'-Dimethylarginine
30344-00-4
|
US $2.00 / KG | 1g | 98%min | ask | Career Henan Chemical Co |
-
- N,N'-Dimethylarginine
30344-00-4
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- SDMA
30344-00-4
- US $34.00-101.00 / mg
- ≥98%
- TargetMol Chemicals Inc.
-
- N,N'-Dimethylarginine
30344-00-4
- US $2.00 / KG
- 98%min
- Career Henan Chemical Co