ChemicalBook >> CAS DataBase List >>5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE
5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE
- CAS No.
- 6508-43-6
- Chemical Name:
- 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE
- Synonyms
- L-152,804;9-(4,4-Dimethyl-2,6-dioxocyclohexyl)-1,2,3,4-tetrahydro-3,3-dimethyl-1-xanthenone;5,5-Mmethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-1,3 cyclohexanedione;5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE;2-(3,3-Dimethyl-1-oxo-2,3,4,9-tetrahydro-1H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione;1,3-Cyclohexanedione, 5,5-dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-
- CBNumber:
- CB9136715
- Molecular Formula:
- C23H26O4
- Molecular Weight:
- 366.45
- MDL Number:
- MFCD00184132
- MOL File:
- 6508-43-6.mol
- MSDS File:
- SDS
Last updated:2024-11-19 23:02:33
5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE Properties
Melting point | 207-208 °C |
---|---|
Boiling point | 513.7±50.0 °C(Predicted) |
Density | 1.20±0.1 g/cm3(Predicted) |
storage temp. | Desiccate at +4°C |
solubility | DMSO: soluble5mg/mL, clear (warmed) |
form | powder |
pka | 4.86±0.42(Predicted) |
color | white to beige |
FDA UNII | AP9351PWPR |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06,GHS09 |
---|---|
Signal word | Danger |
Hazard statements | H301-H410 |
Precautionary statements | P273-P301+P310-P501 |
Hazard Codes | T,N |
Risk Statements | 25-50/53 |
Safety Statements | 45-60-61 |
RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all |
WGK Germany | 3 |
5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE price More Price(16)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML0891 | L-152,804 ≥98% (HPLC) | 6508-43-6 | 5mg | $105 | 2022-05-15 | Buy |
Tocris | 1382 | L-152,804 ≥99%(HPLC) | 6508-43-6 | 10 | $225 | 2021-12-16 | Buy |
Tocris | 1382 | L-152,804 ≥99%(HPLC) | 6508-43-6 | 50 | $927 | 2021-12-16 | Buy |
Usbiological | 255625 | L-152,804 | 6508-43-6 | 10mg | $480 | 2021-12-16 | Buy |
Usbiological | 453113 | L-152,804 | 6508-43-6 | 1mg | $368 | 2021-12-16 | Buy |
5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE Chemical Properties,Uses,Production
Uses
L-152,804 is a potent and orally available Y5 antagonist, which is the receptor postulated to be responsible for hypothalamic "feeding".
Definition
ChEBI: 2-(3,3-dimethyl-1-oxo-4,9-dihydro-2H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione is a member of xanthenes.
Biological Activity
Potent, selective non-peptide neuropeptide Y Y 5 receptor antagonist (K i = 26 nM for hY 5 ). Displays > 300-fold selectivity over hY 1 , hY 2 , and hY 4 receptors. Causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Centrally active upon oral administration in vivo .
storage
Desiccate at +4°C
5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE Preparation Products And Raw materials
Raw materials
Preparation Products
5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE Suppliers
Global( 32)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 4600 | 55 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 3991 | 58 |
Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 3732 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
View Lastest Price from 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE manufacturers
6508-43-6(5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE)Related Search:
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5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE
L-152,804
5,5-Mmethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-1,3 cyclohexanedione
9-(4,4-Dimethyl-2,6-dioxocyclohexyl)-1,2,3,4-tetrahydro-3,3-dimethyl-1-xanthenone
1,3-Cyclohexanedione, 5,5-dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-
2-(3,3-Dimethyl-1-oxo-2,3,4,9-tetrahydro-1H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione
6508-43-6
C23H26O4
Neuropeptide Y (NPY ) receptor