ChemicalBook >> CAS DataBase List >>MDL 72527
MDL 72527
- CAS No.
- 93565-01-6
- Chemical Name:
- MDL 72527
- Synonyms
- CPC-200;MDL 72527;MDL727527;Mdl-72527da;MDL 72527, >=97%;MDL-72527 (MDL72527;MDL 72527, 10 mM in DMSO;MDL 72527 (hydrochloride);N1,N4-Bis(2,3-butadienyl)putrescine;N,N'-Bis(2,3-butadienyl)-1,4-butanediamine
- CBNumber:
- CB91394040
- Molecular Formula:
- C12H20N2.2HCl
- Molecular Weight:
- 0
- MDL Number:
- MFCD13152261
- MOL File:
- 93565-01-6.mol
Last updated:2025-04-17 18:22:24
| Melting point | 236-237 °C (decomp)(Solv: ethanol (64-17-5); ethyl acetate (141-78-6)) |
|---|---|
| storage temp. | Sealed in dry,2-8°C |
| solubility | H2O: soluble15mg/mL, clear |
| form | powder |
| color | light yellow to light brown |
| Water Solubility | H2O: 15mg/mL, clear |
| FDA UNII | 1YVR349GN4 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
MDL 72527 price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M2949 | MDL 72527 ≥98% (HPLC) | 93565-01-6 | 5mg | $118 | 2024-03-01 | Buy |
| Sigma-Aldrich | M2949 | MDL 72527 ≥98% (HPLC) | 93565-01-6 | 25mg | $498 | 2024-03-01 | Buy |
| Cayman Chemical | 13996 | MDL 72527 (hydrochloride) ≥95% | 93565-01-6 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 13996 | MDL 72527 (hydrochloride) ≥95% | 93565-01-6 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 13996 | MDL 72527 (hydrochloride) ≥95% | 93565-01-6 | 10mg | $178 | 2024-03-01 | Buy |
MDL 72527 Chemical Properties,Uses,Production
Uses
MDL 72527 is a lysosomotropic polyamineoxidase inhibitor.
Biological Activity
Polyamine oxidase (POA) inhibitor. Does not inhibit monoamine oxidase or D-Amino acid oxidase. Displays anticancer and neuroprotective activity in vivo .
in vivo
MDL 72527 (100 mg/kg; i.p.; once) shows neuroprotective against neuronal cell damage after temporary focal cerebral ischemia[1].
| Animal Model: | 250-300 g, Male spontaneously hypertensive rats (SHRs)[1] |
| Dosage: | 100 mg/kg |
| Administration: | I.p.; after the induction of ischemia |
| Result: | Significantly reduced meanarterial blood pressure, changed the brain edema formation from 85.7 ± 0.3 to 84.5 ± 0.9% in cortex and from 79.9 ± 1.7 to 78.4 ± 2.0% in subcortex (difference not significant), reduced ischemic injury volume by 22% in the cortex and 17% in the subcortex. |
MDL 72527 Preparation Products And Raw materials
Raw materials
Preparation Products
MDL 72527 Suppliers
Global( 71)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 | |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12984 | 57 | |
| Hangzhou Yuhao Chemical Technology Co., Ltd | 0571-82693216 | info@yuhaochemical.com | China | 9387 | 52 |
N,N'-di(buta-2,3-dien-1-yl)butane-1,4-diaMine
CPC-200
MDL 72527, >=97%
MDL 72527
N,N'-Bis(2,3-butadienyl)-1,4-butanediamine
N,N'-Bis(2,3-butanedienyl)-1,4-butanediamine
N1,N4-Bis(2,3-butadienyl)putrescine
N1,N4-DI(BUTA-2,3-DIENYL)BUTANE-1,4-DIAMINE DIHYDROCHLORIDE
N1,N4-Di(buta-2,3-dienyl)butane-1,4-diamine
N1,N4-Di-2,3-butadienyl-1,4-butanediaminedihydrochloride
Mdl-72527da
N,N'-bis(2,3-Butadienyl)-1,4-butanediamine dihydrochloride
N1,N4-bis(2,3-Butadienyl)-1,4-butanediamine hydrochloride
N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diaMine dihydrochloride
MDL727527
MDL 72527 (hydrochloride)
MDL-72527
(MDL72527
MDL 72527, 10 mM in DMSO
93565-01-6
C12H22Cl2N2