5-Hydroxyindole-2-carboxylic acid
- CAS No.
- 21598-06-1
- Chemical Name:
- 5-Hydroxyindole-2-carboxylic acid
- Synonyms
- 5-HO-ICA;NSC 117338;5-HYDROXY-2-INDOLECARBOXYLIC ACID;5-HYDROXYINDOLE-2-CARBOXYLIC ACID;5-Hydroxyindole-2-carboxylicacid,97%;5-Hydroxy-2-indolecarboxylic acid 98%;5-HYDROXY-1H-INDOLE-2-CARBOXYLIC ACID;5-Hydroxyindole-2-carboxylic acid 98%;5-Hydroxy-2-indolecarboxylic acid,98%;1H-Indole-2-carboxylic acid, 5-hydroxy-
- CBNumber:
- CB9206982
- Molecular Formula:
- C9H7NO3
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD00005615
- MOL File:
- 21598-06-1.mol
- MSDS File:
- SDS
| Melting point | 249 °C (dec.) (lit.) |
|---|---|
| Boiling point | 309.06°C (rough estimate) |
| Density | 1.3312 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | chloroform/ethanol (1:1): soluble50mg/mL, clear to slightly hazy, yellow to brown |
| pka | 4.38±0.30(Predicted) |
| form | Fuming Liquid |
| color | Clear colorless to slightly yellow |
| BRN | 153214 |
| CAS DataBase Reference | 21598-06-1(CAS DataBase Reference) |
| FDA UNII | 5XP5R85YFD |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-21/22 | |||||||||
| Safety Statements | 26-36-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
5-Hydroxyindole-2-carboxylic acid price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 143510 | 5-Hydroxyindole-2-carboxylic acid 98% | 21598-06-1 | 1g | $105 | 2024-03-01 | Buy |
| Sigma-Aldrich | 143510 | 5-Hydroxyindole-2-carboxylic acid 98% | 21598-06-1 | 5g | $177.6 | 2024-03-01 | Buy |
| Alfa Aesar | L00786 | 5-Hydroxyindole-2-carboxylic acid, 97% | 21598-06-1 | 1g | $61.65 | 2024-03-01 | Buy |
| Alfa Aesar | L00786 | 5-Hydroxyindole-2-carboxylic acid, 97% | 21598-06-1 | 5g | $243 | 2024-03-01 | Buy |
| Usbiological | 161918 | 5-Hydroxyindole-2-carboxylic Acid | 21598-06-1 | 2.5g | $425 | 2021-12-16 | Buy |
5-Hydroxyindole-2-carboxylic acid Chemical Properties,Uses,Production
Chemical Properties
light yellow to beige crystalline powder
Uses
5-Hydroxyindole-2-carboxylic acid was used in HPLC-amperometric detection of serotonin in plasma, platelets and urine.
Uses
• ;Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents• ;Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors1• ;Reactant for preparation of melanins as novel nature-inspired radioprotectors2• ;Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity3• ;Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal
Uses
A competitive antagonist of potentiation by glycine at the N-methyl-D-aspartate receptors that have been linked to neuronal death, assiciated to such afflictions as stroke and epilepsy.
Definition
ChEBI: 5-Hydroxyindole-2-carboxylic acid is an indolyl carboxylic acid.
General Description
5-Hydroxyindole-2-carboxylic acid on oxidation with KMnO4 yields pyrrole-2,3,5-tricarboxylic acid.
5-Hydroxyindole-2-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13503 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Unipharm pharmaceutical industry Co., Ltd | 536-8266195 +8613953676784 | lee@unipharm-sd.com | China | 1202 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
View Lastest Price from 5-Hydroxyindole-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | 5-Hydroxyindole-2-carboxylic acid
21598-06-1
|
US $6.60 / KG | 1KG | 97%-99% | 1kg -1000kg | Career Henan Chemical Co |
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- 5-Hydroxyindole-2-carboxylic acid
21598-06-1
- US $6.60 / KG
- 97%-99%
- Career Henan Chemical Co