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EFONIDIPINE

CAS No.
111011-63-3
Chemical Name:
EFONIDIPINE
Synonyms
EFONIDIPINE;Efonidipine(NZ-105);EFONIDIPINE FREE BASE;NZ105,Inhibitor,Ca channels,inhibit,Calcium Channel,NZ 105,Efonidipine,Ca2+ channels;2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate;2-(Benzyl(phenyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate;2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate;5,5-Dimethyl-2-[[1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-[[2-[phenyl(phenylmethyl)amino]ethoxy]carbonyl]pyridin]-3-yl]-1,3,2-dioxaphosphorinane 2-oxide;5-(5,5-Dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid 2-[phenyl(phenylmethyl)amino]ethyl ester;3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester
CBNumber:
CB92130511
Molecular Formula:
C34H38N3O7P
Molecular Weight:
631.66
MDL Number:
MFCD00865899
MOL File:
111011-63-3.mol
Last updated:2024-11-19 23:02:33

EFONIDIPINE Properties

Melting point 169-170℃
Boiling point 746.9±60.0 °C(Predicted)
Density 1.30±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF:30.0(Max Conc. mg/mL);47.49(Max Conc. mM)
Ethanol:40.0(Max Conc. mg/mL);63.32(Max Conc. mM)
form A crystalline solid
pka 4.03±0.50(Predicted)
FDA UNII 40ZTP2T37Q

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H317-H319-H335-H360
Precautionary statements  P201-P261-P280-P305+P351+P338-P308+P313

EFONIDIPINE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0005025 EFONIDIPINE 95.00% 111011-63-3 10MG $224.7 2021-12-16 Buy
CSNpharm CSN16302 Efonidipine 111011-63-3 50mg $307 2021-12-16 Buy
DC Chemicals DC23624 Efonidipine >98% 111011-63-3 1g $1600 2021-12-16 Buy
Crysdot CD31004556 Efonidipine 98+% 111011-63-3 10mg $56 2021-12-16 Buy
Chemenu CM172430 2-(benzyl(phenyl)amino)ethyl5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate 98% 111011-63-3 50mg $209 2021-12-16 Buy
Product number Packaging Price Buy
API0005025 10MG $224.7 Buy
CSN16302 50mg $307 Buy
DC23624 1g $1600 Buy
CD31004556 10mg $56 Buy
CM172430 50mg $209 Buy

EFONIDIPINE Chemical Properties,Uses,Production

Definition

ChEBI: 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate is a carboxylic ester resulting from the formal condensation of the carboxy group of 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid with the hydroxy group of 2-[benzyl(phenyl)amino]ethanol. It is a C-nitro compound, a carboxylic ester, a tertiary amino compound and a dihydropyridine.

111011-80-4
111011-63-3
Synthesis of EFONIDIPINE from 1-(5,5-DiMethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)propan-2-one
Global( 65)Suppliers
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Hubei Jusheng Technology Co.,Ltd.
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career henan chemical co
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TargetMol Chemicals Inc.
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PT CHEM GROUP LIMITED
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GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49978 58

View Lastest Price from EFONIDIPINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Efonidipine pictures 2024-11-19 Efonidipine
111011-63-3
US $31.00-72.00 / mg 99.08% 10g TargetMol Chemicals Inc.
EFONIDIPINE pictures 2019-12-26 EFONIDIPINE
111011-63-3
US $1.00 / KG 1KG ≥98% g/kg/Ton Career Henan Chemical Co
  • Efonidipine pictures
  • Efonidipine
    111011-63-3
  • US $31.00-72.00 / mg
  • 99.08%
  • TargetMol Chemicals Inc.
  • EFONIDIPINE pictures
  • EFONIDIPINE
    111011-63-3
  • US $1.00 / KG
  • ≥98%
  • Career Henan Chemical Co
EFONIDIPINE 5-(5,5-Dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid 2-[phenyl(phenylmethyl)amino]ethyl ester 5,5-Dimethyl-2-[[1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-[[2-[phenyl(phenylmethyl)amino]ethoxy]carbonyl]pyridin]-3-yl]-1,3,2-dioxaphosphorinane 2-oxide EFONIDIPINE FREE BASE Efonidipine(NZ-105) 2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate 2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate 3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester NZ105,Inhibitor,Ca channels,inhibit,Calcium Channel,NZ 105,Efonidipine,Ca2+ channels 2-(Benzyl(phenyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate 111011-63-3 Inhibitors