ChemicalBook >> CAS DataBase List >>1-Fluoro-2-nitrobenzene
1-Fluoro-2-nitrobenzene
- CAS No.
- 1493-27-2
- Chemical Name:
- 1-Fluoro-2-nitrobenzene
- Synonyms
- O-FLUORONITROBENZENE;2-Fluoro-1-nitrobenzene;Fluoronitrobenzene1;uoro-2-nitrobenzene;O-NITROFLUOROBENZENE;2-NITROFLUOROBENZENE;1-Fluoro-2-nitrobenz;2-flouromitrobrnzene;o-fluoronitorobenzene;Olanzapine Impurity 2
- CBNumber:
- CB9213131
- Molecular Formula:
- C6H4FNO2
- Molecular Weight:
- 141.1
- MDL Number:
- MFCD00007048
- MOL File:
- 1493-27-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-10-27 18:05:39
| Melting point | −6 °C (21 °F; 267 K) |
|---|---|
| Boiling point | 215 °C (419 °F; 488 K) |
| Density | 1.3291 g/cm3 |
| vapor pressure | 3.09Pa at 25℃ |
| refractive index | 1.53 |
| Flash point | 94 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Ethyl Acetate, Methanol |
| form | liquid |
| color | colorless |
| Specific Gravity | 1.338 |
| Water Solubility | immiscible |
| BRN | 607262 |
| InChI | 1S/C6H4FNO2/c7-5-3-1-2-4-6(5)8(9)10/h1-4H |
| InChIKey | PWKNBLFSJAVFAB-UHFFFAOYSA-N |
| SMILES | [O-][N+](=O)c1ccccc1F |
| LogP | 1.69 |
| CAS DataBase Reference | 1493-27-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-fluoro-2-nitro-(1493-27-2) |
| EPA Substance Registry System | Benzene, 1-fluoro-2-nitro- (1493-27-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302+H332-H311-H372-H411 | |||||||||
| Precautionary statements | P273-P280-P301+P312-P302+P352+P312-P304+P340+P312-P314 | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,T,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-36/37 | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Toxic/Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29049085 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Aquatic Chronic 2 STOT RE 1 |
|||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
1-Fluoro-2-nitrobenzene price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F10801 | 1-Fluoro-2-nitrobenzene 99% | 1493-27-2 | 50g | $92.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | F10801 | 1-Fluoro-2-nitrobenzene 99% | 1493-27-2 | 250g | $149 | 2026-04-30 | Buy |
| TCI Chemical | F0104 | 2-Fluoronitrobenzene >98.0%(GC) | 1493-27-2 | 25g | $27 | 2026-04-30 | Buy |
| TCI Chemical | F0104 | 2-Fluoronitrobenzene >98.0%(GC) | 1493-27-2 | 100g | $67 | 2026-04-30 | Buy |
| Strem Chemicals | 09-3890 | o-Fluoronitrobenzene | 1493-27-2 | 10g | $36 | 2024-03-01 | Buy |
1-Fluoro-2-nitrobenzene Chemical Properties, Uses, Production
Chemical Properties
clear yellow to brownish liqui
Uses
o-Nitrofluorobenzene is an intermediate in the synthetic preparations of various pharmaceutical goods.
Uses
1-Fluoro-2-nitrobenzene is an intermediate in the synthetic preparations of various pharmaceutical goods.
Synthesis Reference(s)
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Tetrahedron Letters, 26, p. 2233, 1985 DOI: 10.1016/S0040-4039(00)98970-6
Synthesis
Take choline chloride (0.28g,2mmol) and urea (0.12g,2mmol) to form a low eutectic, add o-chloronitrobenzene (2mmol), potassium fluoride (10mmol) and DMSO (2.5ml), heating to 160 , the reaction for 8 hours. Cool down to room temperature, add water 10ml,stir well, add ethyl acetate (10ml×3) to extract the aqueous layer, combine the organic layer, saturated brine wash (10ml×3) the organic layer. MgSO4 drying, spinning evaporation, to get the crude product, separated by column chromatography, to get the product 1 -fluoro-2-nitrobenzene.
1-Fluoro-2-nitrobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
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4-Amino-3-fluorophenol
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1-Fluoro-3-nitrobenzene
1of3
Global Suppliers ( 606)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. | 13396369453 18678026865 | sdfantai@163.com | China | 904 | 58 |
| Weifang Siyuan Chemical Co., Ltd. | 0536-8888106 17663601818 | 2354379876@qq.com | China | 244 | 58 |
| Shandong Xibang Biological Technology Development Co. LTD | 0536-3611186 15063661551 | 196056703@qq.com | China | 59 | 58 |
| Danyang Hengyu Chemical Co., Ltd | 13861235852 | 541510190@qq.com | China | 10 | 58 |
| Shandong Qianyuan Polymer Material Co. , Ltd. | 18678041314 18765609661 | 2547772582@qq.com | China | 995 | 58 |
| Shandong RuiYue Biotechnology Co., Ltd. | 0531-88581623 18805314509 | 1456922171@126.com | China | 63 | 50 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
View Latest Price from 1-Fluoro-2-nitrobenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 1-Fluoro-2-nitrobenzene
1493-27-2
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 1-Fluoro-2-nitrobenzene
1493-27-2
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2021-07-02 | 1-Fluoro-2-nitrobenzene
1493-27-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 1-Fluoro-2-nitrobenzene
1493-27-2
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1-Fluoro-2-nitrobenzene
1493-27-2
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 1-Fluoro-2-nitrobenzene
1493-27-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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2-FLUORONITROBENZENE AKA 1-FLUORO-2-NITROBENZENE
2-FLUORONITROBENZENE 99.5%
1-Fluoro-2-nitrobenzene, 99% 10ML
1-Nitro-2-fluorobenzene
2-Nitro-1-fluorobenzene
o-fluoronitorobenzene
1-Fluoro-2-nitrobenzene,99%
1-Fluoro-2-nitrobenz
2-flouromitrobrnzene
Olanzapine Impurity 2
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1-Fluor-2-nitrobenzol
uoro-2-nitrobenzene
2-Fluoronitrobenzene>
1-Fluoro-2-nitrobenzene ISO 9001：2015 REACH
1-Fluoro-2-nitrobenze
2-Fluoro-1-nitrobenzene
O-FLUORONITROBENZENE
o-Fluoronitrobenzene (1-fluoro-2-nitrobenzene)
1493-27-2
493-27-2
1493-2702
1493-24-2
FC6H4NO2
O2NC6H4F
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