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N-(2-Hydroxyethyl)adenosine

N-(2-Hydroxyethyl)adenosine Structure
N-(2-Hydroxyethyl)adenosine structure
CAS No.
4338-48-1
Chemical Name:
N-(2-Hydroxyethyl)adenosine
Synonyms
NSC 54251;6-Hydroxyethyladenosine;N-(2-Hydroxyethyl)adenosine;N6-(2-Hydroxyethyl)adenosine;Adenosine, N-(2-hydroxyethyl)-;N6-(2-Hydroxyethyl)adenosine, 10 mM in DMSO;(2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4;(2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-di;(2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)aMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
CBNumber:
CB92431540
Molecular Formula:
C12H17N5O5
Molecular Weight:
311.29
MDL Number:
MFCD00056977
MOL File:
4338-48-1.mol
Last updated:2025-04-29 09:03:59
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N-(2-Hydroxyethyl)adenosine Properties

Melting point 194-195℃
Boiling point 725.8±70.0 °C(Predicted)
Density 1.88
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 13.11±0.70(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338-P304+P340-P405-P501

N-(2-Hydroxyethyl)adenosine price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H998120 N-(2-Hydroxyethyl)adenosine 4338-48-1 25mg $95 2021-12-16 Buy
TRC H998120 N-(2-Hydroxyethyl)adenosine 4338-48-1 250mg $305 2021-12-16 Buy
TRC H998120 N-(2-Hydroxyethyl)adenosine 4338-48-1 1g $880 2021-12-16 Buy
Matrix Scientific 096144 (2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 95+% 4338-48-1 1g $1647 2021-12-16 Buy
AK Scientific 5992AB (2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 4338-48-1 1g $2273 2021-12-16 Buy
Product number Packaging Price Buy
H998120 25mg $95 Buy
H998120 250mg $305 Buy
H998120 1g $880 Buy
096144 1g $1647 Buy
5992AB 1g $2273 Buy

N-(2-Hydroxyethyl)adenosine Chemical Properties,Uses,Production

Uses

N-(2-Hydroxyethyl)adenosine has been studied as an anticonvulsant through the activation of adenosine A1 receptor (AA1R).

in vivo

N6-(2-Hydroxyethyl)adenosine (20-40 mg/kg, ip, once daily for 6 weeks) reduces the blood glucose level and diabetes-induced kidney damage, increases the activities of antioxidant enzymes (such as SOD, catalase CAT and GSH) in renal tissue, reduces the level of malondialdehyde (MDA), exhibits anti-inflammatory and antioxidant activities, and ameliorates Alloxan (HY-W017227)-induced diabetes in rats models[2].
N6-(2-Hydroxyethyl)adenosine (75-150 mg/kg, po, once daily for 19 days) exhibits antitumor effect in SGC-7901 xenograft mouse models[4].

Animal Model:Alloxan-induced diabetes in rats models[2]
Dosage:20-40 mg/kg
Administration:ip, once daily for 6 weeks
Result:Reduced the levels of blood glucose, serum creatinine (Scr), blood urea nitrogen (BUN) and urine protein.
Reduced the levels of TNF-α, IL-1β, IL-6, TGF-β1 and NF-κB in kidney tissue.
Alleviated the damage of glomeruli and renal tubules.
Animal Model:SGC-7901 xenograft mouse models[4]
Dosage:75-150 mg/kg
Administration:po, once daily for 19 days
Result:Reduced tumor volume and weight.

N-(2-Hydroxyethyl)adenosine synthesis

96655-92-4
4338-48-1
Synthesis of N-(2-Hydroxyethyl)adenosine from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

N-(2-Hydroxyethyl)adenosine Preparation Products And Raw materials

Raw materials

6-(BETA-HYDROXYETHYLAMINO)-PURINE 6-Hydroxypurine Inosine

Preparation Products

N-(2-Hydroxyethyl)adenosine Suppliers

Global( 103)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3009 60
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29857 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 12185 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9642 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9985 58
changzhou huayang technology co., ltd 		+8615250961469 2571773637@qq.com China 9691 58
Wuhu Nuowei chemistry Co., Ltd. 		+86-0553-2911116-802 +86-18055311600 sales1@nuowei-chem.com China 1638 58
Supplier Advantage
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
Shanghai Zheyan Biotech Co., Ltd. 		58
career henan chemical co 		58
BOC Sciences 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
Finetech Industry Limited 		58
NewCan Biotech Limited 		58
changzhou huayang technology co., ltd 		58
Wuhu Nuowei chemistry Co., Ltd. 		58

View Lastest Price from N-(2-Hydroxyethyl)adenosine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N6-(2-Hydroxyethyl)adenosine pictures 2025-04-29 N6-(2-Hydroxyethyl)adenosine
4338-48-1
 US $32.00-48.00 / mg 99.4% 10g TargetMol Chemicals Inc.
N-(2-Hydroxyethyl)adenosine pictures 2025-04-04 N-(2-Hydroxyethyl)adenosine
4338-48-1
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
N-(2-Hydroxyethyl)adenosine pictures 2019-08-05 N-(2-Hydroxyethyl)adenosine
4338-48-1
 US $5.00 / KG 5KG 99% 1ton Career Henan Chemical Co

N-(2-Hydroxyethyl)adenosine Spectrum

N-(2-Hydroxyethyl)adenosine(4338-48-1)1HNMR

4338-48-1(N-(2-Hydroxyethyl)adenosine)Related Search:

ADP Hydroxyethyl urea
NSC 54251 (2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-di N-(2-Hydroxyethyl)adenosine 6-Hydroxyethyladenosine N6-(2-Hydroxyethyl)adenosine (2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)aMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol (2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4 Adenosine, N-(2-hydroxyethyl)- N6-(2-Hydroxyethyl)adenosine, 10 mM in DMSO 4338-48-1