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LINDERANE

LINDERANE structure

CAS No.: 13476-25-0

Chemical Name:: LINDERANE

Synonyms: linerane;LINDERANE;Linderane-RM;LINDERANE(RG);wuyaomineizhi;Linderane ,98%;Linderane, 98%, from Lindera aggregata (Sims) Kosterm.;(1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-2H-10,1a-(epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one;(1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-10,1a-(epoxymethano)-2H-oxireno[4,5]cyclodeca[1,2-b]furan-12-one;2H-10,1a-(Epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one,3,6,10,10a-tetrahydro-5,9-dimethyl-, (1aS,4E,10S,10aS)-

CBNumber:: CB9243408

Molecular Formula:: C15H16O4

Molecular Weight:: 260.29

MDL Number:: MFCD07781424

MOL File:: 13476-25-0.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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LINDERANE Properties

Melting point	190～191℃
Boiling point	434.5±45.0 °C(Predicted)
Density	1.30±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Stability	Hygroscopic

SAFETY

Risk and Safety Statements

Safety Statements	24/25
HS Code	29322090

LINDERANE price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHL80489	Linderane phyproof? Reference Substance	13476-25-0	10mg	$629	2024-03-01	Buy
Cayman Chemical	27479	Linderane	13476-25-0	5mg	$44	2024-03-01	Buy
Cayman Chemical	27479	Linderane	13476-25-0	10mg	$78	2024-03-01	Buy
Cayman Chemical	27479	Linderane	13476-25-0	25mg	$151	2024-03-01	Buy
Cayman Chemical	27479	Linderane	13476-25-0	50mg	$278	2024-03-01	Buy

Product number	Packaging	Price	Buy
PHL80489	10mg	$629	Buy
27479	5mg	$44	Buy
27479	10mg	$78	Buy
27479	25mg	$151	Buy
27479	50mg	$278	Buy

LINDERANE Chemical Properties,Uses,Production

Description

Linderane is a sesquiterpene that has been found in L. aggregata. It inhibits the cytochrome P450 (CYP) isoform CYP2C9 (K_i = 1.26 μM) in an irreversible and NADPH-dependent manner. Linderane decreases phosphoenolpyruvate carboxykinase (Pck1) and glucose-6-phosphatase (G6pc) gene expression, cAMP concentration, and CREB phosphorylation, increases phosphodiesterase 3 (PDE3) activity, and inhibits gluconeogenesis in rat primary hepatocytes. In vivo, linderane (50 mg/kg twice per day) decreases serum and hepatic triglyceride levels, as well as random-fed and fasting blood glucose levels in ob/ob mice.

Uses

Linderane is a sequiterpene lactone extract from Lindera strychnifolia compound used as a cytotoxic agent against hepaic stellate cells.

Definition

ChEBI: Linderane is a member of dioxanes.

LINDERANE Preparation Products And Raw materials

Raw materials

Preparation Products

LINDERANE Suppliers

Global( 186)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Chongqing Chemdad Co., Ltd	58
Shanghai Standard Technology Co., Ltd.	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from LINDERANE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	Linderane 13476-25-0	US $40.00-129.00 / mg		98.25%	10g	TargetMol Chemicals Inc.
2023-02-24	Linderane 13476-25-0	US $0.00 / mg	5mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.
2023-02-24	Linderane 13476-25-0	US $0.00 / mg	5mg	Analytical Standard	10 g	Shanghai Standard Technology Co., Ltd.

Linderane
13476-25-0
US $40.00-129.00 / mg
98.25%
TargetMol Chemicals Inc.

Linderane
13476-25-0
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

Linderane
13476-25-0
US $0.00 / mg
Analytical Standard
Shanghai Standard Technology Co., Ltd.

LINDERANE Spectrum

LINDERANE(13476-25-0)¹³CNMR

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LINDERANE 2H-10,1a-(Epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one,3,6,10,10a-tetrahydro-5,9-dimethyl-, (1aS,4E,10S,10aS)- (1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-10,1a-(epoxymethano)-2H-oxireno[4,5]cyclodeca[1,2-b]furan-12-one (1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-2H-10,1a-(epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one LINDERANE(RG) Linderane ,98% Linderane, 98%, from Lindera aggregata (Sims) Kosterm. wuyaomineizhi linerane Linderane-RM 13476-25-0 phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract chemical reagent pharmaceutical intermediate