AM1172
- CAS No.
- 251908-92-6
- Chemical Name:
- AM1172
- Synonyms
- AM1172;N-5Z,8Z,11Z,14Z-EICOSATETRAENYL-4-HYDROXY-BENZAMIDE;4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide;N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide;Benzamide, N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxy-
- CBNumber:
- CB9251038
- Molecular Formula:
- C27H39NO2
- Molecular Weight:
- 409.6
- MDL Number:
- MFCD08062148
- MOL File:
- 251908-92-6.mol
| Boiling point | 590.8±50.0 °C(Predicted) |
|---|---|
| Density | 0.983±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in ethanol |
| form | solution in ethanol |
| pka | 8.53±0.26(Predicted) |
| FDA UNII | G5DZB59PZA |
AM1172 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10005223 | AM1172 ≥98% | 251908-92-6 | 5mg | $87 | 2024-03-01 | Buy |
| Cayman Chemical | 10005223 | AM1172 ≥98% | 251908-92-6 | 10mg | $163 | 2024-03-01 | Buy |
| Cayman Chemical | 10005223 | AM1172 ≥98% | 251908-92-6 | 50mg | $680 | 2024-03-01 | Buy |
| Cayman Chemical | 10005223 | AM1172 ≥98% | 251908-92-6 | 100mg | $1189 | 2024-03-01 | Buy |
| Tocris | 3381 | AM1172 ≥98%(HPLC) | 251908-92-6 | 10 | $193 | 2021-12-16 | Buy |
AM1172 Chemical Properties,Uses,Production
Uses
AM 1172 is a potent and selective inhibitor of anandamide uptake and FAAH.
Biological Activity
Metabolically stable anandamide uptake inhibitor (IC 50 = 2.1 - 2.5 μ M) and fatty acid amide hydrolase (FAAH) inhibitor (K i = 3.18 μ M). Inhibits N -arachidonylethanolamine (AEA) accumulation (IC 50 = 24 μ M) and hydrolysis (K i = 3 μ M), and inhibits N -palmitoylethanolamine (PEA) hydrolysis (IC 50 = 36 μ M) in cerebellar granule neurons. Also acts as a non-selective cannabinoid receptor partial agonist (EC 50 values are 189 and 271 nM at CB 2 and CB 1 receptors respectively).
References
1. fegley d, kathuria s, mercier r, et al. anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor am1172. proceedings of the national academy of sciences of the united states of america. 2004;101(23):8756-8761.
AM1172 Preparation Products And Raw materials
Raw materials
Preparation Products
AM1172 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11217 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8617 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4933 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6075 | 58 |