4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
- CAS No.
- 694499-26-8
- Chemical Name:
- 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
- Synonyms
- PON50;SW-53;SWF-53;Ponatinib int2;Ponatinib Impurity 3;Pralsetinib Impurity 1;Intermediate of Ponatinib;4-(4-Methylpiperazinomethyl)-3-;4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline;4-(4-Methylpiperazinomethyl)-4-(trifluoromethyl)aniline
- CBNumber:
- CB92520701
- Molecular Formula:
- C13H18F3N3
- Molecular Weight:
- 273.3
- MDL Number:
- MFCD09909924
- MOL File:
- 694499-26-8.mol
- MSDS File:
- SDS
Boiling point | 329.1±42.0 °C(Predicted) |
---|---|
Density | 1.227 |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
pka | 7.55±0.10(Predicted) |
InChI | InChI=1S/C13H18F3N3/c1-18-4-6-19(7-5-18)9-10-2-3-11(17)8-12(10)13(14,15)16/h2-3,8H,4-7,9,17H2,1H3 |
InChIKey | ZMWAZMYBMAAMAW-UHFFFAOYSA-N |
SMILES | C1(N)=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1 |
FDA UNII | KFW56NE7FT |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302+H332-H315-H319-H335 |
Precautionary statements | P280 |
HS Code | 2933599590 |
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | M329373 | 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline | 694499-26-8 | 5g | $250 | 2021-12-16 | Buy |
Matrix Scientific | 132323 | 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline 97% | 694499-26-8 | 25g | $2700 | 2021-12-16 | Buy |
Apolloscientific | PC51192 | 4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline 95+% | 694499-26-8 | 1g | $17 | 2021-12-16 | Buy |
Oakwood | 212607 | 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline 95% | 694499-26-8 | 1g | $19 | 2021-12-16 | Buy |
SynQuest Laboratories | 3H30-3-3G | 4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline 95.0% | 694499-26-8 | 1g | $28 | 2021-12-16 | Buy |
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Chemical Properties,Uses,Production
Uses
4-(6-Acryloyloxyhexyloxy)-benzoesure (4-cyanophenylester) can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and in the process of chemical and pharmaceutical synthesis.
Synthesis
4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline Into a solution 4-methyl-1-(4-nitro-2-(trifluoromethyl)benzyl)piperazine (1.5 g, 5 mmol) in MeOH (250 mL) was added Raney Nickel (0.15 g, 10 wt %). The suspension was stirred under hydrogen atmosphere (50 psi) for 24 hrs and monitored by TLC. The reaction mixture was filtered through celite and the filtrate was concentrated under reduced pressure to yield the desired product (1.36 g, 100%). 1H NMR (300 MHz, CDCl3) |?: 7.43-7.46 (1H, d, J=9.0 Hz), 6.91 (1H, s), 6.77-6.80 (1H, d J=9.0 Hz), 3.77 (2H, s), 3.54 (2H, s), 2.53 (8H, brs), 2.34 (3H, s).
storage
Store long-term at 2-8°C.
![709045-30-7](/CAS/20210305/GIF/709045-30-7.gif)
![694499-26-8](/CAS/GIF/694499-26-8.gif)
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
PharmOrgSyn Laboratories Co., Ltd. | +86-021-38228826 +86-13916602830 | sales@pharmorgsyn.cn | China | 140 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10977 | 58 |
Unibest Industrial Co.,Ltd. | +86-8657427855777 +86-18758850676 | info@unibestcn.com | China | 227 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | Ethan@dornechem.com | China | 3145 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9332 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Shandonghaohong biotechnology Co.,ltd. | 0635-6175299 13961496334 | sale@inyelchem.com | CHINA | 44 | 55 |
Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
View Lastest Price from 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-25 | 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
694499-26-8
|
US $1.00 / g | 1g | 99% | 100kg | Dorne Chemical Technology co. LTD | |
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2024-08-22 | 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
694499-26-8
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2024-03-28 | 4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline
694499-26-8
|
US $0.00 / KG | 25KG | 98% | Inquiry | PNP Biotech Co. Ltd |
-
- 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
694499-26-8
- US $1.00 / g
- 99%
- Dorne Chemical Technology co. LTD
-
- 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
694499-26-8
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline
694499-26-8
- US $0.00 / KG
- 98%
- PNP Biotech Co. Ltd
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