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VU 0357017 hydrochloride

CAS No.
1135242-13-5
Chemical Name:
VU 0357017 hydrochloride
Synonyms
CS-2319;VU0357017;CID 25010775;SID 56353039;VU0357017 HCI;ML071 hydrochloride;VU 0357017 hydrochloride;VU0357017 monohydrochloride;Ethyl 4-(2-(2-methylbenzamido)ethylamino)piperidine-1-carboxylate hydrochloride;VU0-357017;VU 0357017;CID-25010775; VU-0357017 HYDROCHLORIDE; VU 0357017 HYDROCHLORIDE
CBNumber:
CB92546794
Molecular Formula:
C18H28ClN3O3
Molecular Weight:
369.9
MDL Number:
MFCD17215959
MOL File:
1135242-13-5.mol
MSDS File:
SDS
Last updated:2024-11-19 15:53:33

VU 0357017 hydrochloride Properties

storage temp. Inert atmosphere,2-8°C
solubility DMSO: ≥10mg/mL
form powder
color white to off-white

SAFETY

Risk and Safety Statements

Hazard Codes  N
Risk Statements  52/53
Safety Statements  61
WGK Germany  2

VU 0357017 hydrochloride price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich V4640 VU0357017 monohydrochloride ≥98% (HPLC) 1135242-13-5 5mg $134 2024-03-01 Buy
Sigma-Aldrich V4640 VU0357017 monohydrochloride ≥98% (HPLC) 1135242-13-5 25mg $465 2022-05-15 Buy
Cayman Chemical 11939 VU0357017 (hydrochloride) ≥98% 1135242-13-5 1mg $33 2024-03-01 Buy
Cayman Chemical 11939 VU0357017 (hydrochloride) ≥98% 1135242-13-5 5mg $90 2024-03-01 Buy
Cayman Chemical 11939 VU0357017 (hydrochloride) ≥98% 1135242-13-5 10mg $164 2024-03-01 Buy
Product number Packaging Price Buy
V4640 5mg $134 Buy
V4640 25mg $465 Buy
11939 1mg $33 Buy
11939 5mg $90 Buy
11939 10mg $164 Buy

VU 0357017 hydrochloride Chemical Properties,Uses,Production

Uses

VU0357017 is a subtype-selective M1 muscarinic acetylcholine allosteric agonist. VU0357017 has a potency of 200 nM and Achmax of 81% and had no activity at M2-M5 up to the highest concentrations tested and also had little or no detectable antagonist activity at any other mAChR subtype at concentrations over 2 orders of magnitude higher than those required to activate M1 or activity at a large panel of GPCRs, ion channels, and transporters. In contrast, TBPB inhibited responses to ACh at each of the other mAChR subtypes. VU0357017 was active in reversing cognitive deficits induced by Scopolamine (S200000) in a preclinical rodent model.

Uses

VU 0357017 Hydrochloride is a cholinergic M1 receptor antagonist and a cholinomimetic agent used for the treatment of behavioral and/or mental disorders.

storage

+4°C

VU 0357017 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38632 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76

View Lastest Price from VU 0357017 hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
VU0357017 hydrochloride pictures 2024-11-19 VU0357017 hydrochloride
1135242-13-5
US $56.00-163.00 / mg 99.97% 10g TargetMol Chemicals Inc.
VU 0357017 hydrochloride 4-[[2-[(2-Methylbenzoyl)aMino]ethyl]aMino]-1-piperidinecarboxylic Acid Ethyl Ester Hydrochloride 4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester monohydrochloride CID 25010775 Ethyl 4-(2-(2-methylbenzamido)ethylamino)piperidine-1-carboxylate hydrochloride ML071 hydrochloride SID 56353039 VU0357017 monohydrochloride VU0357017 VU0-357017;VU 0357017;CID-25010775; VU-0357017 HYDROCHLORIDE; VU 0357017 HYDROCHLORIDE CS-2319 VU0357017 HCI Muscarinic acetylcholine receptor,CID 25010775,VU 0357017,muscarinic,Inhibitor,inhibit,VU-0357017 hydrochloride,VU0357017 hydrochloride,VU0357017,mAChR,VU-0357017,CID25010775,acetylcholine,Alzheimer’s,schizophrenia 1135242-13-5 C18H27N3O3HCl Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Positive allosteric modulator of muscarinic M1 receptors. Amines