6-O-Benzylguanine
- CAS No.
- 19916-73-5
- Chemical Name:
- 6-O-Benzylguanine
- Synonyms
- 6-benzylguanine;O6-BENZYLGUANINE;O6-Benzylguanine ,98%;6-(benzyloxy)-7H-purin-2-aMine;O6-BenzyL;NSC 637037;6-O-BENZYLGUANINE;6-BENZYLOXY GUANINE;6-oxo -benzylguanine;4 6-Benzyloxyguanine
- CBNumber:
- CB9263934
- Molecular Formula:
- C12H11N5O
- Molecular Weight:
- 241.25
- MDL Number:
- MFCD00269931
- MOL File:
- 19916-73-5.mol
- MSDS File:
- SDS
Melting point | 193(dec.) |
---|---|
Boiling point | 459.3±55.0 °C(Predicted) |
Density | 1.48±0.1 g/cm3(Predicted) |
storage temp. | room temp |
solubility | methanol: 20 mg/mL |
form | solid |
pka | 7.47±0.20(Predicted) |
color | Off-White to Light Yellow |
CAS DataBase Reference | 19916-73-5(CAS DataBase Reference) |
NCI Dictionary of Cancer Terms | O(6)-benzylguanine |
FDA UNII | 01KC87F8FE |
NCI Drug Dictionary | O6-benzylguanine |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
|
6-O-Benzylguanine price More Price(43)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | B2292 | O6-Benzylguanine ≥98% (TLC), solid | 19916-73-5 | 50mg | $107 | 2024-03-01 | Buy |
Alfa Aesar | H60274 | O6-Benzylguanine, 98% | 19916-73-5 | 250mg | $47.65 | 2024-03-01 | Buy |
Cayman Chemical | 16332 | O6-Benzylguanine ≥98% | 19916-73-5 | 10mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 16332 | O6-Benzylguanine ≥98% | 19916-73-5 | 1g | $699 | 2024-03-01 | Buy |
Cayman Chemical | 16332 | O6-Benzylguanine ≥98% | 19916-73-5 | 50mg | $56 | 2024-03-01 | Buy |
6-O-Benzylguanine Chemical Properties,Uses,Production
Chemical Properties
Light Yellow Solid
Uses
O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Uses
An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.
Biochem/physiol Actions
O6-Benzylguanine (O6BG) inhibits methylguanine methyltransferase (MGMT) by blocking the active site through benzyl group transfer. The use of O6BG with bis-chloroethylnitrosourea (BCNU) or carmustine is effective in treating solid tumors including lymphomas, melanomas and sarcoma.
6-O-Benzylguanine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12495 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20291 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 874 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
View Lastest Price from 6-O-Benzylguanine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-23 | O6-Benzylguanine
19916-73-5
|
US $0.00-0.00 / g | 1g | 99.9% | 20 tons | airuikechemical co., ltd. | ||
2024-09-18 | 6-O-Benzylguanine
19916-73-5
|
US $0.00-0.00 / Kg/Drum | 1KG | 99%min | 1000kgs | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-08-15 | 6-O-Benzylguanine
19916-73-5
|
US $20.00-1.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
- O6-Benzylguanine
19916-73-5
- US $0.00-0.00 / g
- 99.9%
- airuikechemical co., ltd.
- 6-O-Benzylguanine
19916-73-5
- US $0.00-0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- 6-O-Benzylguanine
19916-73-5
- US $20.00-1.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
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