ChemicalBook >> CAS DataBase List >>(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione

(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione

CAS No.
219719-95-6
Chemical Name:
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione
Synonyms
Fluticasone USP RC B;Fluticasone Impurity 54;Fluticasone Propionate RC B;Fluticasone Trioxo Impurity;luticasone Related Compound B;Fluticasone Related CoMpound B;Fluticasone USP Related Compound B;(5'R,6S,8S,9R,10S,11S,13S,14S,16R);Fluticasone Impurity 10(Fluticasone USP RC B);Fluticasone Propionate USP Related Compound B
CBNumber:
CB92694572
Molecular Formula:
C22H24F2O5S
Molecular Weight:
438.48
MDL Number:
MFCD31563235
MOL File:
219719-95-6.mol
Last updated:2023-04-23 13:52:06

(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Properties

Melting point >125°C (dec.)
Boiling point 562.1±60.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka 12.93±0.70(Predicted)
color Off-White to Pale Beige
FDA UNII EP20877CWZ

(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D446130 (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-spiro[androsta-1,4-diene-17,5''-[1,3]oxathiolane]-2'',3,4''-trione 219719-95-6 10mg $95 2021-12-16 Buy
Medical Isotopes, Inc. 69518 (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-spiro[androsta-1,4-diene-17,5??-[1,3]oxathiolane]-2??,3,4??-trione 219719-95-6 500mg $2400 2021-12-16 Buy
Product number Packaging Price Buy
D446130 10mg $95 Buy
69518 500mg $2400 Buy

(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Chemical Properties,Uses,Production

Uses

An impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory. Fluticasone USP Related Compound B.

(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Preparation Products And Raw materials

Raw materials

Preparation Products

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(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Fluticasone Related CoMpound B Fluticasone USP RC B Fluticasone Impurity 10(Fluticasone USP RC B) 6alpha,9alpha-Difluoro-11beta-hydroxy-16alpha-methyl-2',3,4'-trioxo-17alpha-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane) (5R,6'S,8'S,9'R,10'S,11'S,13'S,14'S,16'R)-6',9'-difluoro-11'-hydroxy-10',13',16'-trimethylspiro[1,3-oxathiolane-5,17'-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene]-2,3',4-trione Fluticasone USP Related Compound B/Fluticasone Trioxo Impurity/6α,9α-Difluoro-11β-hydroxy-16α-methyl-2',3,4'-trioxo-17α-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane) (5'R,6S,8S,9R,10S,11S,13S,14S,16R) Fluticasone USP Related Compound B Spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione, 6,9-difluoro-11-hydroxy-16-methyl-, (6α,11β,16α,17α)- (9CI) Fluticasone Related Compound B (Fluticasone Trioxo Impurity) Fluticasone Propionate RC B (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,5'-[1,3]oxathiolane]-2',3,4'(6H)-trione (6a,11β,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-spiro[androsta-1,4-diene-17,5-[1,3]oxathiolane]- Fluticasone Trioxo Impurity (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Fluticasone Propionate USP Related Compound B Spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione, 6,9-difluoro-11-hydroxy-16-methyl-, (6α,11β,16α,17α)- (9CI) Spiro[androsta-1,4-diene-17,5′-[1,3]oxathiolane]-2′,3,4′-trione, 6,9-difluoro-11-hydroxy-16-methyl-, (6α,11β,16α,17α)- Fluticasone Impurity 54 (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-spiro[androstα-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione luticasone Related Compound B 219719-95-6 C22H24F2O5S Pharmaceuticals, Intermediates & Fine Chemicals, Steroids