Triproamylin acetate
- CAS No.
- 187887-46-3
- Chemical Name:
- Triproamylin acetate
- Synonyms
- Symlin;Triproamylin acetate;Pramlintide acetate salt;Pramlintide acetate(151126-32-8 free base);Pramlintide acetate(151126 32 8 free base),Pramlintide acetate(151126328 free base)
- CBNumber:
- CB92717215
- Molecular Formula:
- C173H271N51O55S2
- Molecular Weight:
- 4009.44154
- MDL Number:
- MFCD08460172
- MOL File:
- 187887-46-3.mol
storage temp. | -20°C |
---|---|
form | Solid |
color | White to off-white |
FDA UNII | JS41L76X7I |
UNSPSC Code | 12352200 |
NACRES | NA.77 |
Triproamylin acetate price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML2523 | Pramlintide acetate salt ≥95% (HPLC) | 187887-46-3 | 5mg | $197 | 2024-03-01 | Buy |
Sigma-Aldrich | SML2523 | Pramlintide acetate salt ≥95% (HPLC) | 187887-46-3 | 25mg | $792 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | API0006412 | PRAMLINTIDE ACETATE 95.00% | 187887-46-3 | 100MG | $3031.88 | 2021-12-16 | Buy |
Triproamylin acetate Chemical Properties,Uses,Production
Uses
Pramlintide acetate is a polypeptide analogue of human amylin. Pramlintide acetate, an antidiabetic agent, is antineoplastic in colorectal cancer[1].
Biochem/physiol Actions
Pramlintide (AC0137, AC137, triPro-amylin) is a synthetic antidiabetic peptide that corresponds to human amylin (aa34-70) with proline substitutions at N25, S28 and S29 to limit the self-aggregation seen with native amylin. Pramlintide augments endogenous amylin-mediated glycemic control (blood glucose regulation) in vivo by delaying gastric emptying and inhibiting the secretion of glucagon, a catabolic hormone that opposes the effects of insulin and amylin.
References
[1] Maha S Al-Keilani, et al. Pramlintide, an antidiabetic, is antineoplastic in colorectal cancer and synergizes with conventional chemotherapy. Clin Pharmacol. 2018 Mar 5;10:23-29. DOI:10.2147/CPAA.S153780
Triproamylin acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Triproamylin acetate Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38648 | 58 | |
Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7062 | 58 |
Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 021-51816796-820 13611835272 | sales2@sunwaypharm.com | China | 44455 | 58 |
Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62072 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24739 | 58 |
Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2672 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
Hangzhou Beiputai Biopharmaceutical Co., Ltd | 0571-85350119 15888826472 | bptsales@163.com | China | 3851 | 58 |
Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 48813 | 58 |
View Lastest Price from Triproamylin acetate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-11-19 | Pramlintide acetate(151126-32-8 free base)
187887-46-3
|
US $36.00-137.00 / mg | 100% | 10g | TargetMol Chemicals Inc. |
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- Pramlintide acetate(151126-32-8 free base)
187887-46-3
- US $36.00-137.00 / mg
- 100%
- TargetMol Chemicals Inc.