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PHA-680626

CAS No.
398493-74-8
Chemical Name:
PHA-680626
Synonyms
PHA-680626;Benzamide, 4-(4-methyl-1-piperazinyl)-N-[1,4,5,6-tetrahydro-5-[2-(2-thienyl)acetyl]pyrrolo[3,4-c]pyrazol-3-yl]-
CBNumber:
CB92731123
Molecular Formula:
C23H26N6O2S
Molecular Weight:
450.56
MDL Number:
MFCD19689563
MOL File:
398493-74-8.mol
Last updated:2024-10-28 16:48:35

PHA-680626 Chemical Properties,Uses,Production

Description

PHA-680626 is a potent and selective PLK inhibitor. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases. PHA-680626 inhibits Plk1 (IC50 = 0.53 μM), Plk2 (IC50 = 0.07 μM) and Plk3 (IC50 = 1.61 μM).

PHA-680626 Preparation Products And Raw materials

Raw materials

Preparation Products

PHA-680626 Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18478 58
Shanghai Easy CDMO Co.,Ltd 021-61734564 August@easycdmo.com China 10031 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58

View Lastest Price from PHA-680626 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PHA-680626 pictures 2024-10-28 PHA-680626
398493-74-8
US $1520.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • PHA-680626 pictures
  • PHA-680626
    398493-74-8
  • US $1520.00-1980.00 / mg
  • TargetMol Chemicals Inc.
PHA-680626 Benzamide, 4-(4-methyl-1-piperazinyl)-N-[1,4,5,6-tetrahydro-5-[2-(2-thienyl)acetyl]pyrrolo[3,4-c]pyrazol-3-yl]- 398493-74-8