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PHA-680626
- CAS No.
- 398493-74-8
- Chemical Name:
- PHA-680626
- Synonyms
- PHA-680626;Benzamide, 4-(4-methyl-1-piperazinyl)-N-[1,4,5,6-tetrahydro-5-[2-(2-thienyl)acetyl]pyrrolo[3,4-c]pyrazol-3-yl]-
- CBNumber:
- CB92731123
- Molecular Formula:
- C23H26N6O2S
- Molecular Weight:
- 450.56
- MDL Number:
- MFCD19689563
- MOL File:
- 398493-74-8.mol
Last updated:2024-10-28 16:48:35
PHA-680626 Chemical Properties,Uses,Production
Description
PHA-680626 is a potent and selective PLK inhibitor. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases. PHA-680626 inhibits Plk1 (IC50 = 0.53 μM), Plk2 (IC50 = 0.07 μM) and Plk3 (IC50 = 1.61 μM).
PHA-680626 Preparation Products And Raw materials
Raw materials
Preparation Products
PHA-680626 Suppliers
Global( 4)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19863 | 58 |
Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18478 | 58 |
Shanghai Easy CDMO Co.,Ltd | 021-61734564 | August@easycdmo.com | China | 10031 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19711 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Changzhou Bojia Biomedical Technology Co., Ltd. | 58 |
Shanghai Easy CDMO Co.,Ltd | 58 |
TargetMol Chemicals Inc. | 58 |
View Lastest Price from PHA-680626 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-28 | PHA-680626
398493-74-8
|
US $1520.00-1980.00 / mg | 10g | TargetMol Chemicals Inc. |
- PHA-680626
398493-74-8
- US $1520.00-1980.00 / mg
- TargetMol Chemicals Inc.
PHA-680626
Benzamide, 4-(4-methyl-1-piperazinyl)-N-[1,4,5,6-tetrahydro-5-[2-(2-thienyl)acetyl]pyrrolo[3,4-c]pyrazol-3-yl]-
398493-74-8