Nadic anhydride
- CAS No.
- 826-62-0
- Chemical Name:
- Nadic anhydride
- Synonyms
- NADIC ANHYDRIDE;5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE;NADIC ANHYDRIDE 98%;3A,4,7,7A-TETRAHYDRO-4,7-METHANOISOBENZOFURAN-1,3-DIONE;(3aR,4S,7R,7aS)-3a,4,7,7a-Tetrahydro-4,7-Methanoisobenzofuran-1,3-dione;NA-anhydride;EBDIC ANHYDRIDE;Nadic anhydrous;HIMIC ANHYDRIDE;ENDO-CIS-HIMIC ANHYDRIDE
- CBNumber:
- CB9274095
- Molecular Formula:
- C9H8O3
- Molecular Weight:
- 164.16
- MDL Number:
- MFCD00213361
- MOL File:
- 826-62-0.mol
- MSDS File:
- SDS
| Melting point | 165-167 °C(lit.) |
|---|---|
| Boiling point | 251.61°C (rough estimate) |
| Density | 1.2132 (rough estimate) |
| refractive index | 1.5260 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | diethyl ether: soluble0.1g/10 mL, clear, colorless |
| form | powder to crystal |
| color | White to Almost white |
| Specific Gravity | 1.250 (20/4℃) |
| Merck | 14,1796 |
| BRN | 150228 |
| InChI | InChI=1S/C9H8O3/c10-8-6-4-1-2-5(3-4)7(6)9(11)12-8/h1-2,4-7H,3H2 |
| InChIKey | KNDQHSIWLOJIGP-UHFFFAOYSA-N |
| SMILES | C1(=O)C2C(C3CC2C=C3)C(=O)O1 |
| LogP | -0.040 (est) |
| FDA 21 CFR | 175.105 |
| CAS DataBase Reference | 826-62-0(CAS DataBase Reference) |
| FDA UNII | N1KQO6559B |
| EPA Substance Registry System | 4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydro- (826-62-0) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H318-H334 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338-P342+P311 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 41-42/43 | |||||||||
| Safety Statements | 22-24-26-37/39 | |||||||||
| RIDADR | UN 1325 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DT5600000 | |||||||||
| F | 21 | |||||||||
| HS Code | 38220090 | |||||||||
| Toxicity | skn-rbt 500 mg/24H MLD 28ZPAK -,140,72 | |||||||||
| NFPA 704 |
|
Nadic anhydride price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 14353 | Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride ≥95.0% | 826-62-0 | 250g | $164 | 2024-03-01 | Buy |
| TCI Chemical | N0331 | 5-Norbornene-2,3-dicarboxylic Anhydride >97.0%(T) | 826-62-0 | 25g | $30 | 2024-03-01 | Buy |
| TCI Chemical | N0331 | 5-Norbornene-2,3-dicarboxylic Anhydride >97.0%(T) | 826-62-0 | 500g | $85 | 2024-03-01 | Buy |
| Matrix Scientific | 172490 | Bicyclo[2.2.1]-5-heptene-2,3-dicarboxylic anhydride | 826-62-0 | 100g | $108 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK325920 | 5-Norbornene-2,3-dicarboxylic Anhydride 95% | 826-62-0 | 100g | $53 | 2021-12-16 | Buy |
Nadic anhydride Chemical Properties,Uses,Production
Description
The substance 5-norbornene-2,3-dicarboxylic anhydride has a purity of approximately 99.5 % and consists of two isomers, cis-5-norbrene-endo-2,3-dicarboxylic anhydride (99.2 %) and cis-5-norbreneexo-2,3-dicarboxylic anhydride (0.3 %). It has an estimated log Po/w = 2.3. Due to its chemical nature as an anhydride it readily hydrolyses into the free diacid, norbornene-2,3-dicarboxylic acid. Therefore, migration into aqueous foodstuffs will also lead to the presence of the two isomeric diacids. Melting point of the substance is 163-165 °C.
Chemical Properties
white solid
Uses
5-Norbornene-2,3-dicarboxylic anhydride, as a copolymer monomer in polyester can coatings up to 18.3 % w/w in the final dry coating, does not pose a safety concern to the consumer under sterilised conditions and prolonged contact with all foodstuffs (except beverages).
Application
Nadic anhydride, also known as 5-Norbornene-2,3-dicarboxylic anhydride, is an organic anhydride derivative of norbornene. Besides its use as a component of polyester can coatings in foodstuffs, it is also used as an organic synthesis intermediate. 5-Norbornene-2,3-dicarboxylic anhydride (NA) can lower the cPC content of a polymerization reaction under zinc glutarate catalysis (3 MPa CO2, 60 °C, 0.8 wt% catalyst in neat PO) from 4.5% to about 1%, even if the anhydride concentration is as low as 0.3 mol%.
Reactions
Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride reacts with methyl aminomethyllambertianate to give amide of bicyclo[2.2.1]heptan-1,2-dicarbocylic acid with a labdanoid substituent.
Safety Profile
Mild skin and severe eye irritant.When heated to decomposition it emits acrid smoke andirritating fumes.
Toxicity evaluation
In a cytogenetic test in vitro, 5-norbornene-2,3-dicarboxylic anhydride was clastogenic both in presence and absence of an exogenous metabolic activation system. Gene mutation assays in bacteria and cultured mammalian cells provided negative results. When administered to rats by the oral route at the maximum tolerated dose, 5-norbornene-2,3-dicarboxylic anhydride was not clastogenic/aneugenic in bone marrow, and did not induce DNA damage in liver and at the site of first contact (stomach) in a combined micronucleus and comet assay. It is concluded that the clastogenic activity of 5-norbornene2,3-dicarboxylic anhydride observed in vitro is not expressed in vivo, and that 5-norbornene-2,3- dicarboxylic anhydride does not raise concern for genotoxicity.
Nadic anhydride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Puyang Huicheng Electronic Materials Co., Ltd. | +86-0393-+86-0393-8910800 +8615839383373 | info@huichengchem.com | China | 529 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7709 | 58 |
| Auschemicals Pty Ltd | +61406202619 | info@auschemicals.com | Australia | 426 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8804 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12827 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5887 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20260 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 3712 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29792 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 19918 | 58 |
View Lastest Price from Nadic anhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-18 | Himic anhydride
826-62-0
|
US $10.00 / kg | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2025-02-14 | Himic anhydride
826-62-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-02-08 | Himic anhydride
826-62-0
|
US $28.00 / kg | 1kg | 0.98 | 100kg | Shanghai UCHEM Inc. |
-
- Himic anhydride
826-62-0
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- Himic anhydride
826-62-0
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- Himic anhydride
826-62-0
- US $28.00 / kg
- 0.98
- Shanghai UCHEM Inc.
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